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Table 2 Characteristics at the onset of AFLD or at the last visit of non-AFLD subjects

From: Obesity and metabolic abnormalities as risks of alcoholic fatty liver in men: NAGALA study

 

No AFLD

Incident AFLD

P value

Number

472

168

 

Habitual alcohol consumption, N (%)

209 (44.3)

91 (54.2)

0.027

Exerciser, N (%)

110 (23.3)

24 (14.3)

0.013

Never smoker, N (%)

47 (9.9)

9 (5.4)

0.028

Ex smoker, N (%)

173 (36.7)

79 (47)

 

Current smoker, N (%)

252 (53.4)

80 (47.6)

 

Diabetes, N (%)

28 (5.9)

23 (13.7)

0.0014

High blood pressure, N (%)

234 (49.6)

108 (64.3)

0.001

High blood glucose, N(%)

230 (48.7)

104 (61.9)

0.0033

High triglycerides, N (%)

98 (20.8)

76 (45.2)

< 0.0001

Low HDL-cholesterol, N (%)

42 (8.9)

38 (22.6)

< 0.0001

Age, year

54 (13)

52 (13)

0.043

BMI, kg/m2

22.3 (3.5)

24.2 (3.8)

< 0.0001

Systolic blood pressure, mmHg

127 (20.4)

130 (14.5)

0.0035

Diastolic blood pressure, mmHg

80 (14.5)

83.8 (10.6)

0.0005

Fasting blood glucose, mg/dl

99 (13)

103 (15.8)

0.0003

HbA1c, %

5.2 (0.5)

5.4 (0.7)

0.024

Total cholesterol, mg/dl

198 (47)

204 (43)

0.0023

Triglyserides, mg/dl

85.5 (71)

136 (125.8)

< 0.0001

HDL-cholesterol, mg/dl

59 (23.7)

49.9 (19.7)

< 0.0001

LDL-cholesterol, mg/dl

112.8 (45.8)

119.2 (48.6)

0.027

Non HDL-cholesterol, mg/dl

136.7 (49.8)

153.9 (49)

< 0.0001

AST, IU/L

21 (9)

24 (13)

< 0.0001

ALT, IU/L

20( 11)

25 (17)

< 0.0001

GGT, IU/L

34.5 (36)

50 (59.7)

< 0.0001

Alb, g/dl

4.2 (0.3)

4.3 (0.3)

0.68

Platelet, 104/mL

22.6 (6.8)

23.6 (8.1)

0.13

FIB4index

1.12 (0.7)

1.1 (0.68)

0.29

NAFLD Fibrosis score

− 2.12 (1.49)

− 2.19 (1.63)

0.90

Alcohol consumption, g/week

371 (244.7)

462 (310.9)

0.092

Body weight gain, kg

0.1 (3.6)

1.5 (3.5)

< 0.0001

  1. Data are expressed as frequency (percentages %) for categorical variables, or median (interquartile range) for continuous variables. Comparisons between the groups were performed with the Pearson's chi-square test for categorical variables and with the Mann–Whitney U test or Kruskal–Wallis test for continuous variables
  2. HDL high-density lipoprotein, LDL low-density lipoprotein, BMI body mass index, HbA1c hemoglobin A1c, AST aspartate aminotransferase, ALT alanine aminotransferase, GGT γ-glutamyltransferase, Alb albumin