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Table 4 Multivariable evaluation of APRI sore (> 2.0) and FIB-4 score (> 3.25) to predict liver cirrhosis, adjusted for age and sex

From: Prevalence of sero-markers and non-invasive assessment of liver cirrhosis in patients with Hepatitis B virus infection in Freetown, Sierra Leone: a cross-sectional study

Variables

APRI Score

FIB-4 Score

Crude

OR

95% (CI)

Adjusted OR

95% (CI)

p Value

Crude

OR

95% (CI)

Adjusted OR

95% (CI)

p Value

Clinical features or symptoms of liver cirrhosis

None present

Ref

 

 < 0.001

Ref

  

One or more present

19.8 (4.8–81.7)

20.0 (4.1–85.9)

 

2.0 (0.5–8.5)

–

0.298

Direct bilirubin

Not elevated

Ref

 

0.003

Ref

  

Elevated

11.0 (2.0–53.0)

12.1 (1.9–63.0)

 

1.8 (0.5–6.2)

–

0.348

Total bilirubin

Not elevated

Ref

 

0.001

Ref

  

Elevated

15.6 (3.0–75.0)

16.1 (3.2–80.8)

 

3.7 (1.1–13.3)

3.3 (0.9–11.6)

0.065