| |
NASH
|
Alcoholic liver disease
|
Cryptogenic etiology
|
P value
|
|---|
|
NASH versus Alcoholic liver disease
|
NASH versus cryptogenic etiology
|
Alcoholic liver disease versus cryptogenic etiology
|
|---|
|
n = 29
|
n = 57
|
n = 108
|
|---|
|
Age (years)
|
66 (47–82)
|
71 (54–88)
|
73 (25–85)
|
0.040
|
0.018
|
N.S
|
|
Sex (male/female)
|
14/15
|
55/2
|
84/21
|
< 0.001
|
< 0.001
|
0.004
|
|
Body mass index (kg/m2)
|
24.4 (17.4–31.3)
|
23.6 (15.2–32.4)
|
23.5 (16.0–34.2)
|
NS
|
NS
|
NS
|
|
Antibody to hepatitis B core antigen
|
10 (34.4%)
|
17 (29.8%)
|
34 (31.4%)
|
NS
|
NS
|
NS
|
|
Diabetes mellitus
|
13 (44.8%)
|
30 (54.3%)
|
64 (59.2%)
|
NS
|
NS
|
NS
|
|
Hypertension
|
17 (58.6%)
|
34 (59.6%)
|
71 (65.7%)
|
NS
|
NS
|
NS
|
|
Hyperlipidemia
|
8 (25.5%)
|
15 (26.3%)
|
36 (33.3%)
|
NS
|
NS
|
NS
|
|
AST (IU/L)
|
53 (19–397)
|
56 (19–146)
|
39 (15–308)
|
NS
|
0.041
|
0.035
|
|
ALT (IU/L)
|
58 (17–435)
|
45 (11–175)
|
38 (8–340)
|
0.035
|
0.032
|
0.043
|
|
γ-GTP (IU/L)
|
74 (21–612)
|
82 (18–836)
|
70 (8–583)
|
NS
|
NS
|
NS
|
|
Platelet counts (× 104/μL)
|
15.4 (7–23.6)
|
15.1 (5.2–29.1)
|
18.4 (6.1–43.3)
|
NS
|
0.025
|
0.023
|
|
FIB-4 index
|
3.68 (1.03–17.52)
|
3.28 (1.40–11.37)
|
2.56 (0.47–8.66)
|
NS
|
< 0.001
|
0.002
|
|
ALBI grade 1/2/3
|
17/9/3
|
38/17/2
|
74/32/2
|
NS
|
NS
|
NS
|
- Continuous data are presented as medians and range, and categorical data are presented as numbers of patients
- AST aspartate aminotransferase, ALT alanine aminotransferase; γ-GTP γ-Glutamytranspeptidase, NASH non-alcoholic steatohepatitis, FIB-4 fibrosis-4, ALBI grade albumin-bilirubin grade, NS not significant
