| NASH | Alcoholic liver disease | Cryptogenic etiology | P value | ||
---|---|---|---|---|---|---|
NASH versus Alcoholic liver disease | NASH versus cryptogenic etiology | Alcoholic liver disease versus cryptogenic etiology | ||||
n = 29 | n = 57 | n = 108 | ||||
Age (years) | 66 (47–82) | 71 (54–88) | 73 (25–85) | 0.040 | 0.018 | N.S |
Sex (male/female) | 14/15 | 55/2 | 84/21 | < 0.001 | < 0.001 | 0.004 |
Body mass index (kg/m2) | 24.4 (17.4–31.3) | 23.6 (15.2–32.4) | 23.5 (16.0–34.2) | NS | NS | NS |
Antibody to hepatitis B core antigen | 10 (34.4%) | 17 (29.8%) | 34 (31.4%) | NS | NS | NS |
Diabetes mellitus | 13 (44.8%) | 30 (54.3%) | 64 (59.2%) | NS | NS | NS |
Hypertension | 17 (58.6%) | 34 (59.6%) | 71 (65.7%) | NS | NS | NS |
Hyperlipidemia | 8 (25.5%) | 15 (26.3%) | 36 (33.3%) | NS | NS | NS |
AST (IU/L) | 53 (19–397) | 56 (19–146) | 39 (15–308) | NS | 0.041 | 0.035 |
ALT (IU/L) | 58 (17–435) | 45 (11–175) | 38 (8–340) | 0.035 | 0.032 | 0.043 |
γ-GTP (IU/L) | 74 (21–612) | 82 (18–836) | 70 (8–583) | NS | NS | NS |
Platelet counts (× 104/μL) | 15.4 (7–23.6) | 15.1 (5.2–29.1) | 18.4 (6.1–43.3) | NS | 0.025 | 0.023 |
FIB-4 index | 3.68 (1.03–17.52) | 3.28 (1.40–11.37) | 2.56 (0.47–8.66) | NS | < 0.001 | 0.002 |
ALBI grade 1/2/3 | 17/9/3 | 38/17/2 | 74/32/2 | NS | NS | NS |