Table 1 Characteristics of patients with HCC who were stratified according to etiology of their liver disease

Age (years)

72 (21–90)

58 (31–80)

68 (28–84)

< 0.001

< 0.001

Sex (male/female)

417/97

294/67

841/430

NS

< 0.001

Alcohol consumption

330 (64.2%)

207 (57.3%)

562 (44.2%)

0.024

< 0.001

Antibody to hepatitis B core antigen

179 (34.8%)

361 (100%)

397 (31.2%)

< 0.001

< 0.001

Body mass index (kg/m²)

24.3 (14.3–41.2)

22.8 (14.4–31.7)

22.2 (14.8–33.6)

< 0.001

< 0.001

Diabetes mellitus

286 (55.6%)

73 (20.2%)

373 (29.3%)

< 0.001

< 0.001

Hypertension

277 (53.8%)

82 (22.7%)

527 (41.4%)

< 0.001

< 0.001

Hyperlipidemia

247 (48.0%)

105 (29.0%)

295 (23.2%)

< 0.001

 < 0.001

ALT (IU/l)

47 (6–435)

55 (10–644)

51 (9–847)

< 0.001

< 0.001

Platelet counts (× 10⁴/μL, median)

17.8 (2.7–57.3)

15.6 (1.9–38.1)

11.7 (1.1–28.1)

< 0.001

< 0.001

FIB-4 index

3.89 (0.25–28.31)

4.93 (0.35–34.69)

6.63 (0.69–39.61)

< 0.001

< 0.001

ALBI grade 1/2/3

231/242/41

176/154/31

453/741/77

NS

< 0.001

Child–Pugh grade A/B/C

382/105/27

267/71/23

919/304/48

NS

NS

Antinuclear antibody

68 (13.2%)

46 (12.7%)

188 (14.9%)

NS

NS

Antimitochondrial antibodies

15 (2.9%)

3 (0.8%)

20 (1.6%)

0.032

NS

HCC stage^a (I/II/III/IV)

54/188/141/131

61/103/90/107

332/467/321/142

0.006

< 0.001