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Fig. 2 | BMC Gastroenterology

Fig. 2

From: Genotype–phenotype associations of polymorphisms within the gene locus of NOD-like receptor pyrin domain containing 3 in Swiss inflammatory bowel disease patients

Fig. 2

Individual and cumulative effect of the major alleles of rs10733113, rs4353135 and rs55646866 on ambulatory flare management in UC patients. The graphs show the percentage of UC patients with at least one ambulatory visit for flare management A Homozygous for the major allele, heterozygous or homozygous for the minor allele for rs10733113, rs4353135 and rs55646866. B Depending on the cumulative genetic risk score for carrying the major allele for rs10733113, rs4353135 and rs55646866. In a linear regression model a significant association between the cumulative genetic score and the percentage of patients needing ambulatory flare management could be observed (Odds ratio 2.081; 95% CI − 1.393 to 3.11; p < 0.001). C Age at disease onset is shown within the 25% and 75% percentile (box borders) and outliers (dots) in UC patients.

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