Fig. 2

×20 Liver histology image. Liver sample was obtained at the normalization of coagulation parameters. 1—confluent hepatocyte necrosis; 2—cholestasis with ductular reaction; 3—eosinophilic granulocyte infiltrate. Masson's trichrome staining documented the presence of mild to moderate fibrosis. Immunohistochemistry showed marked activation of Kupffer cells but without plasma cell infiltrate (image not shown)