Fig. 2

Pathohistological examination of gastric and colon biopsy specimens. A Gastric mucosal biopsy taken in 2016 [H&E × 100]; moderate chronic active gastritis with incomplete intestinal metaplasia. Inset: [Giemsa × 100]; moderate H. pylori invasion. B Gastric mucosal biopsy taken in 2017 [H&E × 100]; moderate chronic active gastritis with incomplete intestinal metaplasia. Inset [Giemsa × 100]; moderate H. pylori invasion. C Colon mucosal biopsy performed in 2018 after completion of the 2nd attempt of H. pylori eradication [H&E × 100]; moderate to severe diffuse inflammatory infiltrate; reduction in colonic gland number (black star); Crypt abscesses present, surface mucous production depletion, and reduced columnar epithelium (black arrow). D A follow-up colon mucosal biopsy [H&E × 100]; moderate to severe diffuse inflammatory infiltrate; slight reduction in colonic gland number; surface mucous production depletion and reduced columnar epithelium (black arrow). E Colon mucosal biopsy performed in 2020 [H&E × 100]; moderate to severe diffuse inflammatory infiltrate; surface ulcerations, a slight reduction in colonic gland number; surface mucous production depletion and reduced columnar epithelium (black arrow), gland destruction (black star)