Antimicrobial resistance in patients with decompensated liver cirrhosis and bacterial infections in a tertiary center in Northern Germany

Table 3 Susceptibility of pathogens in period 1 and period 2

Antibiotic agent	Period 1 (01/2012–12/2014)				Period 2 (01/2015–04/2018)				p value
Antibiotic agent	Susceptible		Resistant		Susceptible		Resistant
Overall	n	%	n	%	n	%	n	%
Ampicillin	31	34.4	59	65.6	33	32.4	69	67.6	0.76
Ceftriaxone	32	34.0	62	66.0	26	26.0	74	74.0	0.22
Ciprofloxacin	33	62.3	20	37.7	48	68.6	22	31.4	0.47
Meropenem	56	65.1	30	34.9	62	80.5	15	19.5	0.03
Ascites
Ampicillin	15	41.7	21	58.3	14	29.8	33	70.2	0.26
Ceftriaxone	13	36.1	23	63.9	8	18.2	36	81.8	0.07
Ciprofloxacin	13	68.4	6	31.6	23	63.9	13	36.1	0.74
Meropenem	23	67.6	11	32.4	31	77.5	9	22.5	0.34
Blood
Ampicillin	9	27.3	24	72.7	5	22.7	17	77.3	0.71
Ceftriaxone	10	27.8	26	72.2	6	27.2	16	72.7	0.97
Ciprofloxacin	11	61.1	7	38.9	10	58.8	7	41.2	0.89
Meropenem	19	57.6	14	42.4	15	75.0	5	25.0	0.20
Urine
Ampicillin	7	33.3	14	66.7	14	42.4	19	57.6	0.50
Ceftriaxone	9	40.9	13	59.1	12	35.3	22	64.7	0.67
Ciprofloxacin	9	56.3	7	43.8	15	88.2	2	11.8	0.06
Meropenem	14	73.7	5	26.3	16	94.1	1	5.9	0.18

ISSN: 1471-230X