Fig. 6

Analysis of TGF-β associated gene signatures on drug susceptibility in GIAD. a TGF-β associated gene responses to drugs involved in different pathways; The red dots represent genes, the blue dots represent drugs, the green line indicates high gene expression is sensitive to drugs, and the pink line indicates high gene expression is resistant to drugs. b Volcano plot showed imputed drug response differences in the TGF-β subgroups in GIAD (most samples are ESAD samples); The blue dots indicate significant drug-sensitivity, and the red dots indicate significant drug-resistance (FDR < 0.05). c The correlation between lenalidomide (or IPA-3) and TGF-β score