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Table 1 Clinical manifestations of UC patients with and without TI ulcers

From: Discrete terminal ileal ulcers in patients diagnosed with ulcerative colitis: clinical significance and natural course

Variables

Group A

Group B

p value

(n = 41)

(n = 356)

Age, years, mean (SD)

48.3 (15.3)

48.5 (16.7)

0.909

Age at the diagnosis of UC, years, mean (SD)

39.8 (15.5)

40.0 (15.7)

0.929

Male sex, no. (%)

25 (61.0)

221 (62.1)

1.000

Smoking history, no. (%)

  

0.891

 Never smoker, no. (%)

25 (61.0)

212 (59.6)

 

 Former smoker, no. (%)

11 (26.8)

111 (31.2)

 

 Current smoker, no. (%)

5 (13.2)

33 (9.3)

 

Family history, no. (%)

1 (2.4)

5 (1.4)

0.482

Extraintestinal manifestations, no. (%)

2 (4.9)

47 (13.2)

0.205

Inflammation of the appendix orifice, no. (%)

10 (24.4)

89 (25.0)

1.000

Disease activity at the diagnosis of UC

  

0.851

 Mild/inactive, no (%)

23 (56.1)

199 (55.9)

 

 Moderate, no. (%)

14 (34.1)

130 (36.5)

 

 Severe, no. (%)

4 (9.8)

27 (7.6)

 

Disease extent at the diagnosis of UC

  

0.173

 Proctitis, no. (%)

18 (43.9)

193 (54.2)

 

 Left-sided colitis, no. (%)

11 (26.8)

87 (24.4)

 

 Extensive colitis, no. (%)

12 (29.3)

76 (21.3)

 

Maximal extent, no. (%)

  

0.472

 Proctitis, no. (%)

13 (31.7)

142 (39.9)

 

 Left-sided colitis, no. (%)

14 (34.1)

99 (27.8)

 

 Extensive colitis, no. (%)

14 (34.1)

115 (32.3)

 

Proximal extension, no. (%)

5 (12.2)

69 (19.4)

0.396

Mayo endoscopic score at the last endoscopy

  

1.000

 0–1, no. (%)

29 (70.7)

253 (71.1)

 

 2–3, no. (%)

12 (29.3)

103 (28.9)

 

Ever use of medications

   

 Corticosteroid, no. (%)

23 (56.1)

197 (55.3)

1.000

 Azathioprine/6-MP, no. (%)

16 (39.0)

108 (30.3)

0.286

 Anti-TNF agents, no. (%)

3 (7.3)

19 (5.3)

0.486

Colectomy, no. (%)

1 (2.4)

1 (0.3)

0.196

UC-related hospitalization, no. (%)

13 (31.7)

103 (28.9)

0.719

Relapse during follow-up periods, no. (%)

19 (46.3)

142 (39.9)

0.502

Follow-up duration, months, mean (SD)

78.1 (60.4)

70.1 (59.9)

0.415

  1. TI, terminal ileum; SD, standard deviation; UC, ulcerative colitis; MP, mercaptopurine; TNF, tumor necrosis factor