Variables | Group A | Group B | p value |
---|---|---|---|
(n = 41) | (n = 356) | ||
Age, years, mean (SD) | 48.3 (15.3) | 48.5 (16.7) | 0.909 |
Age at the diagnosis of UC, years, mean (SD) | 39.8 (15.5) | 40.0 (15.7) | 0.929 |
Male sex, no. (%) | 25 (61.0) | 221 (62.1) | 1.000 |
Smoking history, no. (%) | Â | Â | 0.891 |
 Never smoker, no. (%) | 25 (61.0) | 212 (59.6) |  |
 Former smoker, no. (%) | 11 (26.8) | 111 (31.2) |  |
 Current smoker, no. (%) | 5 (13.2) | 33 (9.3) |  |
Family history, no. (%) | 1 (2.4) | 5 (1.4) | 0.482 |
Extraintestinal manifestations, no. (%) | 2 (4.9) | 47 (13.2) | 0.205 |
Inflammation of the appendix orifice, no. (%) | 10 (24.4) | 89 (25.0) | 1.000 |
Disease activity at the diagnosis of UC | Â | Â | 0.851 |
 Mild/inactive, no (%) | 23 (56.1) | 199 (55.9) |  |
 Moderate, no. (%) | 14 (34.1) | 130 (36.5) |  |
 Severe, no. (%) | 4 (9.8) | 27 (7.6) |  |
Disease extent at the diagnosis of UC | Â | Â | 0.173 |
 Proctitis, no. (%) | 18 (43.9) | 193 (54.2) |  |
 Left-sided colitis, no. (%) | 11 (26.8) | 87 (24.4) |  |
 Extensive colitis, no. (%) | 12 (29.3) | 76 (21.3) |  |
Maximal extent, no. (%) | Â | Â | 0.472 |
 Proctitis, no. (%) | 13 (31.7) | 142 (39.9) |  |
 Left-sided colitis, no. (%) | 14 (34.1) | 99 (27.8) |  |
 Extensive colitis, no. (%) | 14 (34.1) | 115 (32.3) |  |
Proximal extension, no. (%) | 5 (12.2) | 69 (19.4) | 0.396 |
Mayo endoscopic score at the last endoscopy | Â | Â | 1.000 |
 0–1, no. (%) | 29 (70.7) | 253 (71.1) |  |
 2–3, no. (%) | 12 (29.3) | 103 (28.9) |  |
Ever use of medications | Â | Â | Â |
 Corticosteroid, no. (%) | 23 (56.1) | 197 (55.3) | 1.000 |
 Azathioprine/6-MP, no. (%) | 16 (39.0) | 108 (30.3) | 0.286 |
 Anti-TNF agents, no. (%) | 3 (7.3) | 19 (5.3) | 0.486 |
Colectomy, no. (%) | 1 (2.4) | 1 (0.3) | 0.196 |
UC-related hospitalization, no. (%) | 13 (31.7) | 103 (28.9) | 0.719 |
Relapse during follow-up periods, no. (%) | 19 (46.3) | 142 (39.9) | 0.502 |
Follow-up duration, months, mean (SD) | 78.1 (60.4) | 70.1 (59.9) | 0.415 |