Table 4 Relationship of SMAD4 gene and clinicopathologic characteristics of colorectal cancer
Features | Experimental group | Control group | OR (95% CI) | P value |
|---|---|---|---|---|
Age (years) | < 65 | ≥ 65 | 1.01 (0.91, 1.12) | 0.854 |
Gender | Female | Male | 1.09 (0.95, 1.24) | 0.212 |
Tumor location | Colon | Rectum | 1.15 (1.01, 1.31) | 0.042 |
TNM stage | IV | I–III | 1.28 (1.03, 1.58) | 0.025 |
Tumor grade | Well to moderate | Poor | 1.04 (0.96, 1.12) | 0.318 |
MSI | Stable | Unstable | 1.10 (0.95, 1.28) | 0.191 |
RAS | Mut | WT | 2.13 (1.37, 3.34) | 0.001 |
BRAF | Mut | WT | 1.00 (0.90,1.09) | 0.976 |
Lymph node metastasis | N1 + N2 | N0 | 1.42 (1.20,1.67) | 0.000 |
Mucinous differentiation | Mucinous | Other | 2.23 (1.85,2.70) | 0.000 |