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Table 3 Changes in clinical, endoscopic, and histologic evidence of disease by subject

From: Daily, oral FMT for long-term maintenance therapy in ulcerative colitis: results of a single-center, prospective, randomized pilot study

 

Study code

Age

Sex

Extent of disease

Duration of disease (yrs)

Maintenance therapy

BMI

Change in total Mayo score

Change in endoscopic UCEIS score

Change in endoscopic Mayo score

Change in histologic score

Change in fecal calprotectin (mcg/g)

Change in total IBDQ score

FMT

E

46

F

Pan-colitis

5.5

Mesalamine

20.9

 − 7

 − 2

0

 − 3

 − 285

92

W

35

M

Pan-colitis

7.5

Vedolizumab

27.8

 − 3

 − 1

0

 − 1.3

 − 189

47

F

20

M

Pan-colitis

3.8

Mesalamine

25

 − 1

 − 1

0

 − 2

 − 164

16

A

65

F

L-sided

26.2

Mesalamine

20.9

3

0

1

 − 1.2

? =  > 375

8

N

44

M

Pan-colitis

0.2

Sulfasalazine

25.6

1

 − 3

0

0.9

 > 1000 =  > > 1000

59

P

38

M

Pan-colitis

10.2

Mercaptopurine

25.2

 − 3

2

 − 1

0

 − 42

32

Placebo

B

68

M

Pan-colitis

4.4

Mesalamine

28.8

 − 2

 − 1

0

0.8

 − 132

21

G

58

M

L-sided

27.8

Mesalamine

26.9

1

0

0

 − 2

4

32

Y

65

M

L-sided

0.4

Mesalamine

36.15

0

0

0

0

74

4

V

47

F

Pan-colitis

8.8

Adalimumab

29.2

 − 1

0

0

0

27

35

T

31

F

Pan-colitis

0.8

Mesalamine

29.1

0

 − 1

0

0

 − 137

32

I

40

F

Pan-colitis

16.3

Mesalamine

25

Dropped out due to worsening disease activity

  1. IBDQ, Inflammatory Bowel Disease Questionnaire; L-Sides, left-sided disease; BMI, Body Mass Index; yrs, years; wks, weeks
  2. ^Ulcerative Colitis Endoscopic Index of Severity
  3. *Geboes Score