Table 2 Use of montelukast (MK) as part of an initial combination therapy in eosinophilic gastroenteritis (EGE)
From: Successful use of montelukast in eosinophilic gastroenteritis: a case report and a literature review
Authors | Study design | Number of patients, gender (M%), mean age ± SD (years) | Affected segments | Medications used, duration (if known) | Outcomes: EGE symptoms, tissue eosinophilia and follow-up duration (if reported) |
|---|---|---|---|---|---|
Priyadarshni et al. [16] | Case report | One M, 28 | Stomach and small bowel | Prednisone and montelukast (dose/duration: not reported) | Symptoms resolved |
Hui and Hui [15] | Prospective | 64, M 63%, 40.5 ± 23.5b | Terminal ileum and/or colon | Ketotifen 1 mg daily up to 2 mg twice daily and montelukast 10 mg daily, 16 weeks | Symptoms resolved in 57 of 64 (89.1%) |
Chen et al. [17] | Care report | One M, 54 | Stomach and duodenum | Methylprednisolone 30 mg daily and montelukast 4 mg daily, 1 month | Symptoms resolved, Eosinophilia improved |
Wong et al. [11] | Retrospective case seriesa | One M, – | – | Prednisolone 30–40 mg/day tapered over 1–3 months and montelukast (MK dose/duration: unknown) | Symptoms and eosinophilia resolved, 36 months |
Baek et al. [18] | Case report | One F, 68 | Duodenum | Prednisolone 30 mg daily, 1 month Montelukast 10 mg daily, 5 months | Symptoms and eosinophilia resolved |
Milić et al. [19] | Case report | One F, 30 | Esophagus, stomach, small and large intestine | Prednisone 40 mg daily Montelukast 10 mg daily, 2 weeks | Symptoms resolved |
Pediatric cases | |||||
Tien et al. [12] | Retrospective case seriesa | 8, M 63%, 7.9 ± 6.5b | Stomach and duodenum | Corticosteroids (CS) 1–2 mg/kg/day CS and MK in 6/8 CS and MK and Ketotifen in 2/8, Duration: unknown | 1/8 (12.5%) in remission (on CS and MK) |