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Table 1 Patients’ characteristics at different radiotherapy duration

From: Comparing neoadjuvant long-course chemoradiotherapy with short-course radiotherapy in rectal cancer

Clinical variable

Radiotherapy duration

χ2

P value

SC (%)

LC (%)

Age Median (IQR), years

59 (49–65)

53 (45–60)

0.01*

Sex

Male

Female

18 (56.25)

14 (43.75)

87 (63.04)

51 (36.96)

0.51

0.48**

Distance to anus

 ≤ 5 cm

 > 5 cm

23 (71.88)

9 (28.12)

85 (61.59)

53 (38.41)

1.19

0.28**

Mode of operation

Open abdomen

Endoscopic

6 (18.75)

26 (81.25)

73 (52.90)

65 (47.10)

12.18

 < 0.01**

Type of operation

Dixon

Hartmann

Miles

20 (62.50)

0 (0.00)

12 (37.50)

87 (63.04)

4(2.90)

47(34.06)

0.93***

Neoadjuvant chemotherapy

No

Yes

5 (15.63)

27 (84.37)

36 (26.09)

102 (73.91)

1.55

0.21**

CEA Median (IQR), ng/mL

2.74 (1.55–5.39)

3.95 (1.81–15.27)

0.11*

Clinical tumor stage

cT2

cT3

cT4

4 (12.50)

23 (71.88)

5 (15.62)

4 (2.90)

97 (70.29)

37 (26.81)

5.42

0.08**

Lymph node status

Negative

Positive

2 (6.25)

30 (93.75)

20 (14.49)

118 (85.51)

0.92

0.34**

  1. CEA, carcinoembryonic antigen; SC, short-course radiotherapy; LC, Long-course chemoradiotherapy; IQR, interquartile range
  2. *: Mann–Whitney U test, **: χ2 test, ***: Fisher exact test