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Table 4 Prognosis of patient with signet ring cell carcinoma stratified by treatment

From: Clinicopathological characteristics and prognosis of signet ring cell carcinoma of the gallbladder

Variables N Age, years
 > 60
Male AJCC
III—IV stage
5-year OS
(%)
HR (95% CI) P value
Whole group 278       
CT alone 32 25 (78.1%) 4 (12.5%) 22 (68.8%) 0 Reference  
Surgery alone 153 122 (79.7%) 39 (25.5%) 37 (24.2%) 7.8 0.605 (0.403–0.909) 0.015
Surgery + RT 14 13 (92.9%) 6 (42.9%) 1 (7.1%) 0 0.478 (0.244–0.937) 0.032
Surgery + CT 79 50 (63.3%) 15 (19.0%) 27 (34.2%) 8.6 0.433 (0.279–0.671)  < 0.001
Surgery group 246       
Surgery alone 153 122 (79.7%) 39 (25.5%) 37 (24.2%) 7.8 Reference  
Surgery + RT 14 13 (92.9%) 6 (42.9%) 1 (7.1%) 0 0.802 (0.444–1.451) 0.467
Surgery + CT 79 50 (63.3%) 15 (19.0%) 27 (34.2%) 8.6 0.726 (0.538–0.980) 0.036
  1. OS overall survival, HR hazard ratio, CI confidence interval, CT chemotherapy, RT radiotherapy,
  2. AJCC American Joint Committee on Cancer