Table 6 Year-on-year trend analyses of LT etiologies by HCC status: 2001–2019
NASH | HCV | HBV | Other | |||||
|---|---|---|---|---|---|---|---|---|
With HCC | Without HCC | With HCC | Without HCC | With HCC | Without HCC | With HCC | Without HCC | |
Spearman rank correlation | ||||||||
ρ | 0.66 | 0.75 | − 0.51 | − 0.73 | 0.25 | 0.43 | 0.61 | − 0.11 |
p value | 0.002 | 0.000 | 0.025 | 0.000 | 0.300 | 0.069 | 0.005 | 0.652 |
Joinpoint regression | ||||||||
p < 0.05* | p < 0.05 | p < 0.05* | p < 0.05 | NS | NS | NS | NS | |
2011–2019 APC: 10.4% | 2004–2012 APC: 24.5% | 2006–2019 APC: − 4.9% | 2010–2019 APC: − 12.5% | |||||
Incidence rate ratio | ||||||||
IRR | 1.16 | 1.08 | 0.94 | 0.91 | 1.00 | 1.02 | 1.12 | 1.00 |
95% CI | 1.07–1.26 | 1.04–1.12 | 0.90–0.98 | 0.89–0.94 | 0.95–1.06 | 0.98–1.05 | 0.95–1.31 | 0.98–1.03 |
p value | < 0.001 | < 0.001 | 0.002 | < 0.001 | 0.873 | 0.414 | 0.171 | 0.768 |