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Table 4 Distribution of primary LT etiologies before and after the availability of direct-acting antivirals

From: Changing trends in liver transplantation indications in Saudi Arabia: from hepatitis C virus infection to nonalcoholic fatty liver disease

 

NASH

HCV

HBV

Other

Pre-DAA

80 (17.6%)

178 (39.1%)

98 (21.5%)

99 (21.8%)

Post-DAA

168 (30.3%)

109 (19.7%)

126 (22.7%)

151 (27.3%)

IRR

    

IRR

1.72

0.50

1.06

1.25

95% CI

1.32–2.25

0.40–0.64

0.81–1.37

0.97–1.61

p value

 < 0.001

 < 0.001

0.686

0.081

  1. IRR compares pre- and post-DAA periods
  2. LT, liver transplant; NASH, Nonalcoholic steatohepatitis; HCV, Hepatitis C virus; HBV, Hepatitis B virus; DAA, Direct-acting antiviral; IRR, incidence rate ratio; CI, confidence interval