Table 2 Cases with ICPIs-associated granulomatous/sarcoid-like reactions in organs other than GI tract
Source | ICPIs used | Affected organ(s) | Malignancy | Patients with G/SLR/total patients |
|---|---|---|---|---|
Johncilla et al. [9] | Ipi or Ipi + Nivo | Liver | MM | 4/11 |
Belliere et al. [10] | Nivo | Kidneys | LC | 1/3 |
Firwana et al. [11] | Ipi or Pembro | Spleen, LN, Skin | CC, MM | 3/3 |
Cousin et al. [12] | Pembro | LN, Lung | LM | 1/10* |
Tetzlaff et al. [13] | Ipi or Pembro | Skin, LN | MM | 3/3 |
De Martin et al. [14] | Ipi + Nivo or Ipi or Pembro | Liver | MM, BC | 7/16 |
Faviez et al. [15] | Ipi + Nivo or Durva | Lung, LN, Spleen | LC, MM | 3/3 |
Kubicki et al. [16] | Ipi or Ipi + BRAF inh | Skin | MM | 3/3 |
Wang et al. [17] | Pembro | Skin, Lung | MM | 1/17 |
Larsen et al. [18] | Pembro or Nivo | Lung | SqCC of skin, MCC, LC | 3/9 |
Rodriguez et al. [19] | Ipi or Nivo or Ipi + Nivo or Ipi + Pembro | LN | MM | 5/5 |
Zen et al. [20] | Atezo | Liver | LC | 2/10 |
Chorti et al. [21] | Nivo or Ipi + Nivo | LN, Lung, Skin, Bone | MM | 8/45 |