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Table 1 Clinical characteristics and pathological/immunohistological findings

From: Immunohistochemical staining for IMP3 in patients with duodenal papilla tumors: assessment of the potential for diagnosing endoscopic resectability and predicting prognosis

 

Adenoma

n = 5

Adenocarcinoma

Tis and T1

T1

T2

T3

(no infiltration in the sphincter of Oddi)

n = 5

(infiltration in the sphincter of Oddi)

n = 3

n = 5

n = 7

Treatment

 Endoscopic papillectomy

5

4

1

1

0

 Surgical operation

0

1

2

4

7

Tumor differentiation

 Well

5

2

2

0

 Moderate

0

1

3

5

 Poor

0

0

0

2

Lymphatic invasion

0

0

2

6

Venous invasion

0

0

2

5

Lymph node metastasis

0

0

2

7

Histological category

 Intestinal

5

3

3

3

1

 Pancreatobiliary

0

0

0

0

4

 Unclassifiable

0

2

0

2

2

IMP3-positive cells (%) in resected specimen, median (range)

5 (0–5)

5 (0–30)

50 (0–70)

20 (5–70)

20 (0–90)

IMP3-positive cell rate ≥ 10%

0

20

66.7

80

71.4

IMP3-positive cells (%) in biopsy specimens, median (range)

5 (0–80)

10 (0–30)

5 (0–60)

60 (0–100)

50 (15–100)a

IMP3-positive cell rate ≥ 10%

20

60

33.3

80

100a

  1. IMP3 insulin-like growth factor 2 mRNA protein 3
  2. aOne patient with T3 adenocarcinoma was excluded because the biopsy had been performed at another hospital