Men | Women | |||||
---|---|---|---|---|---|---|
Past (n = 4279) | Current (n = 8918) | p value | Past (n = 2502) | Current (n = 7361) | p value | |
Age (years old) | 47.0 (16.0) | 48.0 (16.0) | 0.563 | 45.7 (10.1) | 47.3 (14.0) | < 0.001 |
Body mass index (kg/m2) | 23.0 (3.5) | 23.5 (4.0) | < 0.001 | 21.7 (3.0) | 21.4 (3.9) | < 0.001 |
Obesity | 20.4 (870) | 23.4 (2087) | < 0.001 | 11.7 (292) | 10.5 (771) | 0.096 |
Systolic blood pressure (mmHg) | 122.8 (22.5) | 121.3 (19.5) | < 0.001 | 115.6 (18.5) | 112.3 (21.0) | < 0.001 |
Diastolic blood pressure (mmHg) | 77.3 (14.5) | 75.4 (15.5) | < 0.001 | 71.5 (11.2) | 67.3 (15.0) | < 0.001 |
Hypertension | 1.1 (48) | 0.9 (82) | 0.275 | 0.9 (23) | 0.5 (34) | 0.001 |
Fasting plasma glucose (mmol/L) | 5.4 (0.7) | 5.8 (0.7) | < 0.001 | 5.0 (0.9) | 5.3 (0.6) | < 0.001 |
Hyperglycemia | 21.6 (919) | 42.2 (3759) | < 0.001 | 9.5 (237) | 16.3 (1195) | < 0.001 |
Triglycerides (mmol/L) | 1.6 (1.0) | 1.1 (0.7) | < 0.001 | 1.0 (0.6) | 0.7 (0.4) | < 0.001 |
Hypertriglyceridemia | 33.5 (1432) | 12.2 (1091) | < 0.001 | 9.4 (234) | 2.3 (170) | < 0.001 |
High-density lipoprotein cholesterol (mmol/L) | 1.2 (0.4) | 1.5 (0.4) | < 0.001 | 1.4 (0.5) | 1.9 (0.6) | < 0.001 |
Low high-density lipoprotein cholesterol levels | 35.5 (1505) | 7.2 (638) | < 0.001 | 37.4 (926) | 6.0 (439) | < 0.001 |
Aspartate aminotransferase (IU/L) | 21.8 (6.0) | 19.1 (9.0) | < 0.001 | 18.6 (4.0) | 15.5 (7.0) | < 0.001 |
Alanine aminotransferase (IU/L) | 21.7 (12.0) | 23.5 (13.0) | < 0.001 | 13.3 (6.0) | 13.9 (14.8) | 0.003 |
Gamma-glutamyltransferase (IU/L) | 45.7 (34.0) | 31.3 (33.4) | < 0.001 | 17.2 (10.0) | 14.5 (6.5) | 0.036 |
Smoking status | ||||||
Never smoker | 21.6 (905) | 37.2 (3269) | < 0.001 | 85.0 (2079) | 85.9 (6285) | 0.293 |
Ex-smoker | 25.5 (1068) | 33.4 (2941) | < 0.001 | 4.7 (116) | 8.8 (646) | < 0.001 |
Current smoker | 52.9 (2217) | 29.4 (2585) | < 0.001 | 10.3 (251) | 5.3 (389) | < 0.001 |
Habit of exercise | 18.0 (771) | 20.3 (1792) | 0.002 | 18.4 (459) | 16.2 (1176) | 0.013 |
Alcohol consumption, g/week | 131.4 (154.0) | 95.4 (125.0) | < 0.001 | 27.3 (36.0) | 24.9 (12.0) | 0.172 |
Nonalcoholic | 78.9 (3374) | 85.2 (7602) | < 0.001 | 96.0 (2403) | 95.2 (7009) | 0.083 |
(None or minimal) | 51.2 (2189) | 63.4 (5656) | < 0.001 | 81.5 (2039) | 84.7 (6234) | < 0.001 |
(Light) | 27.7 (1185) | 21.8 (1946) | < 0.001 | 14.5 (364) | 10.5 (775) | < 0.001 |
Intermediate | 15.3 (653) | 10.8 (967) | < 0.001 | 2.8 (71) | 2.9 (214) | 0.858 |
Alcoholic | 5.9 (252) | 3.9 (349) | 0.002 | 1.1 (28) | 1.9 (138) | 0.008 |
Fatty liver | 22.5 (963) | 31.2 (2785) | < 0.001 | 8.4 (211) | 9.9 (721) | 0.035 |
NAFLD | 18.5 (792) | 27.1 (2412) | < 0.001 | 8.0 (199) | 9.4 (691) | 0.024 |
NAFLD fibrosis score | − 2.27 (1.13) | − 2.38 (1.19) | < 0.001 | − 2.22 (1.05) | − 2.60 (1.08) | < 0.001 |
Fib4 index | 1.08 (0.51) | 0.93 (0.53) | < 0.001 | 1.07 (0.45) | 0.88 (0.47) | < 0.001 |