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Table 2 Cox regression analysis of overall survival in patients with hepatocellular carcinoma of different BCLC stages

From: Surgical resection significantly promotes the overall survival of patients with hepatocellular carcinoma: a propensity score matching analysis

Variable BCLC stage 0 (N = 66) BCLC stage A (N = 865) BCLC stage B (N = 575) BCLC stage C (N = 810)
HR (95 % CI) P value HR (95 % CI) P value HR (95 % CI) P value HR (95 % CI) P value
Sex
 Female 1   1   1   1  
 Male 0.70 (0.85–1.98) 0.79 0.81 (0.64–1.03) 0.09 0.95 (0.68–1.31) 0.76 0.90 (0.67–1.21) 0.49
Age (years)
 < 60 1   1   1   1  
 ≥ 60 0.83 (0.61–1.11) 0.22 0.84 (0.64–1.09) 0.19 0.71 (0.50–1.01) 0.06 0.81 (0.59–1.09) 0.17
Smoking
 Yes 1   1   1   1  
 No 0.52 (0.22–1.23) 0.14 0.59 (0.08–4.41) 0.61 0.89 (0.37–2.20) 0.82 0.81 (0.30–2.19) 0.68
Alcohol use
 Yes 1   1   1   1  
 No 0.70 (0.10–6.25) 0.67 0.75 (0.10–5.59) 0.78 0.82 (0.55–1.22) 0.33 0.52 (0.19–1.42) 0.20
HBV  
 Negative 1   1   1   1  
 Positive 0.30 (0.04–1.21) 0.25 0.22 (0.03–1.62) 0.14 0.43 (0.27–0.71) 0.001 0.40 (0.27–0.58) < 0.001
HCV
 Negative 1   1     1  
 Positive 0.95 (0.73–1.10) 0.49 0.51 (0.07–3.78) 0.51 0.88 (0.66–1.18) 0.41 0.89 (0.41–1.12) 0.35
Cirrhosis
 Absent 1   1   1   1  
 Present 0.60 (0.42–0.72) 0.006 0.55 (0.39–0.78) 0.001 0.91 (0.59–1.40) 0.66 0.87 (0.53–1.43) 0.58
Child-Pugh class
 A    1   1   1  
 B    0.55 (0.43–0.71) < 0.001 0.41 (0.28–0.61) < 0.001 0.40 (0.29–0.55) < 0.001
Tumor size 0.98 (0.97–1.01) 0.238 1.06 (0.94–1.20) 0.289 1.03 (0.92–1.15) 0.609 0.98 (0.96–1.01) 0.238
Tumor number 0.95 (0.96–1.02) 0.058 1.01 (0.83–1.20) 0.971 1.06 (0.91–1.24) 0.391 0.94 (0.94–1.05) 0.052
Treatment
 Non-surgery 1   1   1   1  
 Surgery 2.31 (1.22–4.61) 0.019 1.41 (1.17–1.70) < 0.001 2.10 (1.56–2.82) < 0.001 3.10 (2.02–4.70) < 0.001
  1. BCLC stage: Barcelona clinic liver cancer; HR: Hazard ratio; CI: Conference incidence; HBV: Hepatitis B virus; HCV: Hepatitis C virus