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Table 1 Baseline characteristics

From: Efficacy and safety of selective internal radiation therapy with yttrium-90 for the treatment of unresectable hepatocellular carcinoma

Variables

N = 97 (%)

Age, years

  < 65

61 (62.9)

  ≥ 65

36 (37.1)

Sex

 Male

90 (92.8)

 Female

7 (7.2)

Etiology

 Hepatitis B

54 (55.7)

 Hepatitis C

4 (4.1)

 Alcohol

3 (3.1)

 Unknown

36 (37.1)

Performance status

 0

14 (14.4)

 1

71 (73.2)

 2

12 (12.4)

Prior treatment

 None

78 (80.4)

 Resection

5 (5.2)

 Radiofrequency ablation

3 (3.1)

 Percutaneous ethanol injection therapy

2 (2.1)

 Transarterial chemoembolization

9 (9.3)

Method of diagnosis

 Liver biopsy

59 (60.8)

 Imaging

38 (39.2)

Pathology

 Well-differentiated

10 (10.3)

 Moderate differentiated

38 (39.2)

 Poorly differentiated

3 (3.1)

 No defined

8 (8.2)

Cirrhosis on imaging

 Present

94 (96.9)

 Absent

3 (3.1)

Tumor distribution

 Unilobar, right

74 (76.3)

 Unilobar, left

7 (7.2)

 Bilobar

16 (16.5)

Portal vein invasion

 None

36 (37.1)

 Below subsegmental

1 (1.0)

 Subsegmental

28 (28.9)

 Lobar

25 (25.8)

 Main

7 (7.2)

Index lesion size (cm)

 < 5

6 (6.2)

 5–10

40 (41.2)

 > 10

51 (52.6)

Tumor burden* (%)

 < 25

44 (45.4)

 25–50

38 (39.2)

 > 50

9 (9.3)

 No defined

6 (6.2)

Alpha-fetoprotein

 < 100

45 (46.4)

  ≥ 100

52 (53.6)

Total bilirubin (mg/dL)

 < 2

93 (95.9)

 2–-3

4 (4.1)

 > 3

0 (0)

Albumin (mg/dL)

 > 3.5

83 (85.6)

 2.8–3.5

12 (12.4)

 < 2.8

2 (2.1)

Child–Pugh class

A

91 (93.8)

B

6 (6.2)

 C

0 (0)

BCLC stage

 A

0 (0)

 B

38 (39.2)

 C

59 (60.8)

 D

0 (0)

  1. *Tumor burden, Tumor volume/liver volume
  2. BCLC, Barcelona Clinic Liver Cancer staging system