Table 3 Factors associated with varices among 250 patients with periportal fibrosis
Variable | Esophageal varices present | Un adjusted | Adjusted | |||
|---|---|---|---|---|---|---|
No, (n = 141) | Yes, (n = 109) | OR (95%CI) | P-value | OR (95%CI) | P-value | |
Age, years* | 42 [35–55] | 39 [33–47] | 0.9 (0.8–1.0) | 0.169 | 1.0 (0.9–1.01) | 0.498 |
Sex | ||||||
Female | 39 ( 27.7) | 31 (28.4) | 1.0 | - | - | |
Male | 102 (72.3) | 78 ( 71.6) | 1.0 (0.5–1.7) | 0.892 | - | - |
Married | ||||||
No | 17 (12.1) | 18 (16.5) | 1.0 | - | - | |
Yes | 124 (87.9) | 91 (83.5) | 0.7 (0.3–1.4) | 0.316 | - | - |
Alcohol use | ||||||
No | 63 (44.7) | 64 ( 58.7) | 1.0 | |||
Yes | 78 (55.3) | 45 ( 41.3) | 0.6 (0.3–0.9) | 0.028 | 0.6 (0.3–1.1) | 0.109 |
S. mansoni test | ||||||
Negative | 21 (14.9) | 7 ( 6.4) | 1.0 | |||
Positive | 120 (85.1) | 102 (93.6) | 2.5 (1.0–6.2) | 0.040 | 2.4 (0.9–7.0) | 0.095 |
Hepatitis B test | ||||||
Negative | 116 (82.3) | 90 (82.6) | 1.0 | - | - | |
Positive | 25 (17.7) | 19 (17.4) | 0.9 (0.5–1.8) | 0.951 | - | - |
APRI levels* | ||||||
< 1.51 | 114 (80.8) | 37 (33.9) | 1.0 | |||
> 1.51 | 27 (19.2) | 72 (66.1) | 8.2 (4.6–14.6) | < 0.001 | 5.8 (3.1–11.1) | < 0.001 |
PCSDR levels** | ||||||
> 5700 | 106 (75.2) | 39 (26.6) | 1.0 | |||
< 5700 | 35 (24.8) | 80 (73.4) | 8.3 (4.7–14.7) | < 0.001 | 5.9 (3.2–11.2) | < 0.001 |
PVD (CM) | 1.5 [1.4–1.7] | 1.5 [1.3–1.7] | 0.9 (0.7–1.2) | 0.858 | ||
SPD (CM) | 17 [15–18.3] | 1.0 (0.9–1.1) | 0.467 | |||
Ascites present | ||||||
No | 62 ( 44.0) | 33 (30.3) | 1.0 | |||
Yes | 79 ( 56.0) | 76 (69.7) | 1.8 (1.1–3.1) | 0.028 | 1.3 (0.7–2.5) | 0.469 |