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Table 1 Socio-demographic and clinical characteristics of the study cohorts

From: Schistosoma mansoni-related periportal fibrosis; can we use APRI and PSDR levels in the real-time selection of patients for targeted endoscopy in a resource-limited setting? A case–control study

Variable

Derivation cohort (N = 250)

Validation cohort (N = 200)

 

Freq

% (95% CI)/median(IQR)

Freq

% (95% CI)/median(IQR)

SEX

 Male

180

72.0 (65.9–77.5)

145

72.5 (65.7–78.5)

 Female

70

28.0 (22.5–34.1)

55

27.5 (21.4–34.2)

Age (Years)

250

41 [33–51]

200

40 [33–49]

Married

 Yes

215

86.0 (81.1–90.1)

168

84.0 (78.1–88.8)

 No

35

14.0 (10.0–18.9)

32

16 (11.1–21.8)

Laboratory

 AST(U/L)

250

39.8 [34–56]

200

40.5 [34–58]

 ALT(U/L)

250

32.5 [19–54]

200

32.5 [20.5–53.8]

 PTC (*103/µL)

250

99 [70–158]

200

100 [66–170]

 S. mansoni+

222

88.8 (84.2–92.4)

180

90 (85.0–93.8)

 HBsAg+

44

17.6 (13.1–22.9)

36

18 (12.9–24.0)

UTS abdomen

 Ascites

155

62.0 (55.7–68.0)

130

65.0 (58.0–71.6)

 PVD (cm)

250

1.5 [1.4–1.7]

200

1.5 [1.4–1.7]

 SPD (cm)

250

17 [15–18]

200

17 [16–19]

Endoscopy

 Varices present

109

43.6 (37.4–49.9)

94

47 (40.0–54.2)

 Varices absent

141

56.3 (5.0–62.6)

106

53 (45.8–60.0)

  1. ALT: alanine aminotransferase; AST: aspartate aminotransferase; HGB: hemoglobin; HBV: hepatitis B Virus; IQR: interquartile range; PTC: platelet counts; PVD: portal vein diameter; SPD: Splenic diameter