Univariable | p value | Multivariable | p value | |
---|---|---|---|---|
Chloride, per 1 mEq/L increase | 0.96 (0.94–0.97) | < 0.001 | 0.94 (0.91–0.98) | 0.002 |
Sodium, per 1 mEq/L increase | 0.97 (0.95–0.99) | 0.010 | 1.03 (0.99–1.08) | 0.119 |
Age per year increase | 1.01 (1.00–1.02) | 0.098 | 1.02 (1.01–1.04) | 0.002 |
Gender | ||||
Female | 1 [Reference] | 1 [Reference] | ||
Male | 0.83 (0.62–1.13) | 0.234 | 0.86 (0.60–1.24) | 0.422 |
Ethnicity | ||||
Other | 1 [Reference] | 1 [Reference] | ||
White | 0.52 (0.37–0.73) | < 0.001 | 0.73 (0.47–1.13) | 0.155 |
Black | 0.64 (0.36–1.17) | 0.150 | 1.03 (0.49–2.19) | 0.935 |
Hispanic | 0.20 (0.08–0.51) | 0.001 | 0.40 (0.13–1.18) | 0.098 |
ICU type | ||||
MICU | 1 [Reference] | |||
SICU/TSICU | 0.89 (0.64–1.23) | 0.481 | ||
CCU/CSRU | 1.14 (0.70–1.85) | 0.604 | ||
Etiology of cirrhosis | ||||
Non-alcoholic | 1 [Reference] | |||
Alcoholic | 1.28 (0.96–1.70) | 0.097 | ||
Elixhauser comorbidity index, per point increase | 1.03 (1.02–1.04) | < 0.001 | 1.01 (0.99–1.02) | 0.243 |
MELD score, per point increase | 1.10 (1.09–1.12) | < 0.001 | 1.04 (1.01–1.06) | 0.007 |
SOFA score, per point increase | 1.39 (1.32–1.45) | < 0.001 | 1.20 (1.12–1.30) | < 0.001 |
Mechanical ventilation | ||||
No | 1 [Reference] | 1 [Reference] | ||
Yes | 3.29 (2.4–4.48) | < 0.001 | 2.61 (1.74–3.90) | < 0.001 |
Vasopressors | ||||
No | 1 [Reference] | 1 [Reference] | ||
Yes | 4.81 (3.55–6.53) | < 0.001 | 1.42 (0.93–2.17) | 0.103 |
Renal replacement therapy | ||||
No | 1 [Reference] | 1 [Reference] | ||
Yes | 5.60 (3.15–9.97) | < 0.001 | 0.63 (0.30–1.32) | 0.221 |
Acute kidney injury | ||||
No | 1 [Reference] | 1 [Reference] | ||
Yes | 3.81 (2.77–5.23) | < 0.001 | 1.56 (1.03–2.37) | 0.037 |
Hemoglobin, per 1 g/dL increase | 0.90 (0.83–0.97) | 0.005 | 0.94 (0.86–1.03) | 0.189 |
Platelet, per 1 × 109/L increase | 1.00 (1.00–1.00) | 0.004 | 1.00 (1.00–1.00) | 0.473 |
White blood cell, per 1 × 109/L increase | 1.05 (1.03–1.07) | < 0.001 | 1.04 (1.01–1.06) | 0.008 |