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Table 4 Hazard ratios for liver related events in Cohort-A with available prognostic data (n = 64) derived from Cox Proportional-Hazards model analyses

From: The Enhanced Liver Fibrosis test maintains its diagnostic and prognostic performance in alcohol-related liver disease: a cohort study

 

ELF cut-offs

Unadjusted HRs (95% CI)

P value

HRs adjusted for age and sex (95% CI)

P value

ELF as continuous (overall)

n/a

1.39 (1.22–1.59)

 < 0.001

1.44 (1.25–1.66)

 < 0.001

ELF split into four categories

 < 9.8 (reference)

1

1

1

1

9.8–10.49

1.68 (0.34–8.31)

0.528

1.49 (0.287–7.74)

0.634

10.5–11.29

4.45 (1.09–10.05)

 < 0.05

3.84 (0.90–16.39)

0.069

 11.3

10.00 (2.97–33.68)

 < 0.001

10.24 (2.97–35.27)

 < 0.001

ELF split into two categories

 < 10.5

1

1

1

1

 10.5

6.49 (2.67–15.78)

 < 0.001

6.42 (2.63–15.24)

 < 0.001

Ishak split into three categories

 < 3 (reference)

1

1

1

1

3–4

2.99 (0.50–17.88)

0.231

3.05 (0.51–18.34)

0.222

5–6

9.88 (2.35–41.56)

 < 0.005

10.45 (2.46–44.34)

 < 0.05

Ishak split into two categories

0–4

1

1

1

1

5–6

5.93 (2.28–15.39)

 < 0.001

6.202 (2.37–16.21)

 < 0.001