Fig. 2

AUROC Curves for Cohort-A (dashed line) and Cohort-NA (solid line) for (a) cirrhosis (F ≧ 5) and (b) moderate fibrosis (F ≧ 3). P values indicate significance of difference between aetiologies (De Long’s test). All values are expressed as % (95% CI). *p > 0.05 ^F012[n(Cohort-A) = 18; n(Cohort-NA) = 416] versus F3456[n(Cohort-A) = 63; n(Cohort-NA) = 289]; + F0123[n(Cohort-A) = 22; n(Cohort-NA) = 515] versus F456[n(Cohort-A) = 59); n(Cohort-NA) = 190]; &F01234[n(Cohort-A) = 27; n(Cohort-NA) = 579] versus F56[n(Cohort-A) = 54; n(Cohort-NA) = 126). Penalty functions (Obuchowski) were assigned proportional to the difference in Ishak units between stages as follows: 0.17, 0.33, 0.50, 0.67, 0.83 and 1.00 for differences of 1, 2, 3, 4, 5, and 6 stages