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Table 4 Analysis of prognostic factors in the super-elderly group

From: Clinical and therapeutic features and prognostic factors of metastatic colorectal cancer over age 80: a retrospective study

Variables

Univariate analysis

Multivariate analysis

Hazard ratio (95% CI)

P value

Hazard ratio (95% CI)

P value

Sex (male/female)

0.85 (0.43–1.66)

0.63

  

PS score of 2–4

2.07 (0.99–4.29)

0.052

0.98 (0.35–2.75)

0.98

Tumor located on the right side

1.23 (0.59–2.57)

0.58

  

Albumin level ≤ 3.5 g/dL

1.56 (0.80–3.07)

0.19

  

BMI ≤ 18.5

1.74 (0.66–4.54)

0.26

  

PNI ≤ 35

6.15 (2.00–18.9)

0.001

8.57 (2.63–27.9)

0.0003

Creatinine level ≥ 1.5 mg/dL

1.78 (0.61–5.20)

0.29

  

CEA level ≥ 5 ng/mL

1.85 (0.91–3.77)

0.089

2.27 (1.09–4.74)

0.03

RAS mutation type

1.20 (0.36–4.02)

0.76

  

Poorly differentiated cancer or signet-ring cell carcinoma

0.64 (0.28–1.51)

0.3

  

Resection of primary tumor

0.41 (0.18–0.92)

0.026

0.45 (0.20–1.04)

0.06

Chemotherapy

0.68 (0.32–1.47)

0.33