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Table 5 Summary of predictive values of fecal biomarkers for endoscopic remission (MES 0 vs. 1, 2, 3)

From: Extent of disease affects the usefulness of fecal biomarkers in ulcerative colitis

FC AUC Cut-off value Sensitivity Specificity PPV NPV Accuracy
All cases 0.821 290 0.713 0.885 0.911 0.651 0.778
Pancolitis 0.866 344 0.761 0.909 0.921 0.732 0.823
Left-side colitis 0.836 192 0.781 0.941 0.970 0.64 0.828
Proctitis 0.649 270 0.571 0.818 0.8 0.6 0.68
FIT AUC Cut-off value Sensitivity Specificity PPV NPV Accuracy
All cases 0.858 45 0.762 0.902 0.928 0.696 0.815
Pancolitis 0.835 42 0.804 0.879 0.902 0.763 0.835
Left-side colitis 0.913 46 0.805 0.941 0.971 0.667 0.845
Proctitis 0.825 25 0.714 0.909 0.909 0.714 0.8
FL AUC Cut-off value Sensitivity Specificity PPV NPV Accuracy
All cases 0.855 79 0.733 0.918 0.937 0.675 0.802
Pancolitis 0.894 79 0.783 0.909 0.923 0.75 0.835
Left-side colitis 0.870 65 0.756 0.941 0.969 0.615 0.810
Proctitis 0.698 98 0.5 0.909 0.875 0.588 0.68
  1. FC fecal calprotectin, FIT fecal immunochemical test for hemoglobin, FL fecal lactoferrin, AUC area under the curve, PPV positive predictive value, NPV negative predictive value