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Table 4 Summary of predictive values of fecal biomarkers for endoscopic remission (MES 0, 1 vs. 2, 3)

From: Extent of disease affects the usefulness of fecal biomarkers in ulcerative colitis

FC AUC Cut-off value Sensitivity Specificity PPV NPV Accuracy
All cases 0.891 298 0.897 0.779 0.693 0.931 0.821
Pancolitis 0.951 403 1 0.824 0.757 1 0.886
Left-sided colitis 0.882 142 1 0.697 0.714 1 0.828
Proctitis 0.645 185 0.8 0.6 0.333 0.923 0.64
FIT AUC Cut-off value Sensitivity Specificity PPV NPV Accuracy
All cases 0.908 195 0.862 0.846 0.758 0.917 0.852
Pancolitis 0.915 283 0.893 0.882 0.807 0.938 0.886
Left-sided colitis 0.926 195 0.88 0.879 0.846 0.906 0.879
Proctitis 0.76 30 0.8 0.7 0.4 0.933 0.72
FL AUC Cut-off value Sensitivity Specificity PPV NPV Accuracy
All cases 0.903 96 0.914 0.798 0.716 0.943 0.840
Pancolitis 0.946 95 0.964 0.804 0.730 0.976 0.861
Left-sided colitis 0.925 111 0.92 0.818 0.793 0.931 0.862
Proctitis 0.6 98 0.6 0.75 0.375 0.882 0.72
  1. FC fecal calprotectin, FIT fecal immunochemical test for hemoglobin, FL fecal lactoferrin, AUC area under the curve, PPV positive predictive value, NPV negative predictive value