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Table 4 Summary of predictive values of fecal biomarkers for endoscopic remission (MES 0, 1 vs. 2, 3)

From: Extent of disease affects the usefulness of fecal biomarkers in ulcerative colitis

FC

AUC

Cut-off value

Sensitivity

Specificity

PPV

NPV

Accuracy

All cases

0.891

298

0.897

0.779

0.693

0.931

0.821

Pancolitis

0.951

403

1

0.824

0.757

1

0.886

Left-sided colitis

0.882

142

1

0.697

0.714

1

0.828

Proctitis

0.645

185

0.8

0.6

0.333

0.923

0.64

FIT

AUC

Cut-off value

Sensitivity

Specificity

PPV

NPV

Accuracy

All cases

0.908

195

0.862

0.846

0.758

0.917

0.852

Pancolitis

0.915

283

0.893

0.882

0.807

0.938

0.886

Left-sided colitis

0.926

195

0.88

0.879

0.846

0.906

0.879

Proctitis

0.76

30

0.8

0.7

0.4

0.933

0.72

FL

AUC

Cut-off value

Sensitivity

Specificity

PPV

NPV

Accuracy

All cases

0.903

96

0.914

0.798

0.716

0.943

0.840

Pancolitis

0.946

95

0.964

0.804

0.730

0.976

0.861

Left-sided colitis

0.925

111

0.92

0.818

0.793

0.931

0.862

Proctitis

0.6

98

0.6

0.75

0.375

0.882

0.72

  1. FC fecal calprotectin, FIT fecal immunochemical test for hemoglobin, FL fecal lactoferrin, AUC area under the curve, PPV positive predictive value, NPV negative predictive value