Skip to main content

Table 2 Proportions of abnormal metabolic features and elevated liver enzymes among 139,170 participants

From: Prevalence of and risk factors for metabolic associated fatty liver disease in an urban population in China: a cross-sectional comparative study

Characteristics Total (N = 139,170) Non-obese subjects (N = 97,079) Obese with MAFLD (n [%]) (N = 25,163) P value
With MAFLD (n [%]) (N = 36,306) Without MAFLD (n [%]) (N = 102,864) P value Non-obese with MAFLD (n [%]) (N = 11,143) Non-obese without MAFLD (n [%]) (N = 85,936) P value
Elevated waist circumference 23,038 (63.5) 18,840 (18.3)  < 0.001 3337 (29.9) 8238 (9.6)  < 0.001 19,701 (78.3)  < 0.001
Elevated systolic pressure 18,610 (51.3) 25,477 (24.8)  < 0.001 4999 (44.9) 18,163 (21.1)  < 0.001 13,611 (54.1)  < 0.001
Elevated diastolic pressure 13,487 (37.1) 14,824 (14.4)  < 0.001 3334 (29.9) 10,158 (11.8)  < 0.001 10,153 (40.3)  < 0.001
Elevated triglycerides 23,574 (64.9) 20,044 (19.5)  < 0.001 7182 (64.5) 14,143 (16.5)  < 0.001 16,392 (65.1) 0.204
Reduced HDL-C 10,042 (27.7) 12,336 (12.0)  < 0.001 3046 (27.3) 9301 (10.8)  < 0.001 6996 (27.8) 0.359
Elevated fasting glucose 17,165 (47.3) 21,259 (20.7)  < 0.001 5347 (48.0) 15,835 (18.4)  < 0.001 11,818 (47.0) 0.073
Elevated total cholesterol 15,287 (42.1) 28,121 (27.3)  < 0.001 4885 (43.8) 22,537 (26.2)  < 0.001 10,402 (41.3)  < 0.001
Elevated LDL-C (mmol/L) 16,386 (45.1) 25,543 (24.8)  < 0.001 5114 (45.9) 19,641 (22.9)  < 0.001 11,272 (44.8) 0.052
Elevated ALT 15,426 (42.5) 11,443 (11.1)  < 0.001 3816 (34.2) 8032 (9.3)  < 0.001 11,610 (46.1)  < 0.001
Elevated AST 3443 (9.5) 2593 (2.5)  < 0.001 774 (6.9) 1963 (2.3)  < 0.001 2669 (10.6)  < 0.001
  1. Data were described by proportions (%). P values were derived from chi-square test
  2. Elevated waist circumference: ≥ 90 cm for men and ≥ 80 cm for women. Elevated systolic pressure: ≥ 130 mmHg. Elevated diastolic pressure: ≥ 85 mmHg. Elevated triglycerides: ≥ 1.70 mmol/L. Reduced HDL-C: < 1.0 mmol/L for men and < 1.3 mmol/L for women. Elevated fasting glucose: ≥ 5.6 mmol/L. Elevated total cholesterol: ≥ 5.2 mmol/L. Elevated LDL-C: ≥ 3.4 mmol/L. Elevated ALT: > 35 IU/L. Elevated AST: > 40 IU/L
  3. MAFLD metabolic associated fatty liver disease, HDL-C high-density lipoprotein cholesterol, LDL-C low-density lipoprotein cholesterol, ALT alanine aminotransferase, AST aspartate aminotransferase
  4. The P value was calculated from the comparation between the groups of Obese with MAFLD (25,163) and Non-obese with MAFLD (11,143)