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Table 2 Proportions of abnormal metabolic features and elevated liver enzymes among 139,170 participants

From: Prevalence of and risk factors for metabolic associated fatty liver disease in an urban population in China: a cross-sectional comparative study

Characteristics

Total (N = 139,170)

Non-obese subjects (N = 97,079)

Obese with MAFLD (n [%]) (N = 25,163)

P value†

With MAFLD (n [%]) (N = 36,306)

Without MAFLD (n [%]) (N = 102,864)

P value

Non-obese with MAFLD (n [%]) (N = 11,143)

Non-obese without MAFLD (n [%]) (N = 85,936)

P value

Elevated waist circumference

23,038 (63.5)

18,840 (18.3)

 < 0.001

3337 (29.9)

8238 (9.6)

 < 0.001

19,701 (78.3)

 < 0.001

Elevated systolic pressure

18,610 (51.3)

25,477 (24.8)

 < 0.001

4999 (44.9)

18,163 (21.1)

 < 0.001

13,611 (54.1)

 < 0.001

Elevated diastolic pressure

13,487 (37.1)

14,824 (14.4)

 < 0.001

3334 (29.9)

10,158 (11.8)

 < 0.001

10,153 (40.3)

 < 0.001

Elevated triglycerides

23,574 (64.9)

20,044 (19.5)

 < 0.001

7182 (64.5)

14,143 (16.5)

 < 0.001

16,392 (65.1)

0.204

Reduced HDL-C

10,042 (27.7)

12,336 (12.0)

 < 0.001

3046 (27.3)

9301 (10.8)

 < 0.001

6996 (27.8)

0.359

Elevated fasting glucose

17,165 (47.3)

21,259 (20.7)

 < 0.001

5347 (48.0)

15,835 (18.4)

 < 0.001

11,818 (47.0)

0.073

Elevated total cholesterol

15,287 (42.1)

28,121 (27.3)

 < 0.001

4885 (43.8)

22,537 (26.2)

 < 0.001

10,402 (41.3)

 < 0.001

Elevated LDL-C (mmol/L)

16,386 (45.1)

25,543 (24.8)

 < 0.001

5114 (45.9)

19,641 (22.9)

 < 0.001

11,272 (44.8)

0.052

Elevated ALT

15,426 (42.5)

11,443 (11.1)

 < 0.001

3816 (34.2)

8032 (9.3)

 < 0.001

11,610 (46.1)

 < 0.001

Elevated AST

3443 (9.5)

2593 (2.5)

 < 0.001

774 (6.9)

1963 (2.3)

 < 0.001

2669 (10.6)

 < 0.001

  1. Data were described by proportions (%). P values were derived from chi-square test
  2. Elevated waist circumference: ≥ 90 cm for men and ≥ 80 cm for women. Elevated systolic pressure: ≥ 130 mmHg. Elevated diastolic pressure: ≥ 85 mmHg. Elevated triglycerides: ≥ 1.70 mmol/L. Reduced HDL-C: < 1.0 mmol/L for men and < 1.3 mmol/L for women. Elevated fasting glucose: ≥ 5.6 mmol/L. Elevated total cholesterol: ≥ 5.2 mmol/L. Elevated LDL-C: ≥ 3.4 mmol/L. Elevated ALT: > 35 IU/L. Elevated AST: > 40 IU/L
  3. MAFLD metabolic associated fatty liver disease, HDL-C high-density lipoprotein cholesterol, LDL-C low-density lipoprotein cholesterol, ALT alanine aminotransferase, AST aspartate aminotransferase
  4. †The P value was calculated from the comparation between the groups of Obese with MAFLD (25,163) and Non-obese with MAFLD (11,143)
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BMC Gastroenterology

ISSN: 1471-230X

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