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Table 1 Baseline characteristics of the study participants

From: Prevalence of and risk factors for metabolic associated fatty liver disease in an urban population in China: a cross-sectional comparative study

Characteristics

Total (N = 139,170)

Male (N = 78,176)

Female (N = 60,994)

P value†

MAFLD (N = 36,306)

Non-MAFLD (N = 102,864)

P value

MAFLD (N = 27,684)

Non-MAFLD (N = 50,492)

P value

MAFLD (N = 8622)

Non-MAFLD (N = 52,372)

P value

Age (years)

47 (19)

42 (21)

 < 0.001

45 (18)

43 (22)

 < 0.001

54 (19)

41 (20)

 < 0.001

 < 0.001

Gender, male (%)

27,684 (76.3)

50,492 (49.1)

 < 0.001

–

–

–

–

–

–

–

BMI (kg/m2)

26.18 (3.41)

22.27 (3.69)

 < 0.001

26.35 (3.24)

23.05 (3.43)

 < 0.001

25.59 (3.70)

21.48 (3.35)

 < 0.001

 < 0.001

Waist circumference (cm)

89 (9)

78 (12)

 < 0.001

91 (9)

82 (10)

 < 0.001

84 (9)

73 (9)

 < 0.001

 < 0.001

Systolic pressure (mmHg)

130 (24)

117 (22)

 < 0.001

130 (22)

121 (21)

 < 0.001

132 (28)

112 (21)

 < 0.001

 < 0.001

Diastolic pressure (mmHg)

81 (15)

72 (14)

 < 0.001

82 (15)

75 (15)

 < 0.001

78 (16)

69 (13)

 < 0.001

 < 0.001

Fasting glucose (mmol/L)

5.5 (1.0)

5.1 (0.7)

 < 0.001

5.5 (1.0)

5.2 (0.6)

 < 0.001

5.6 (1.0)

5.1 (0.6)

 < 0.001

 < 0.001

Total cholesterol (mmol/L)

5.02 (1.22)

4.64 (1.16)

 < 0.001

4.98 (1.20)

4.68 (1.13)

 < 0.001

5.13 (1.30)

4.61 (1.18)

 < 0.001

 < 0.001

Triglycerides (mmol/L)

2.04 (1.43)

1.10 (0.72)

 < 0.001

2.12 (1.50)

1.26 (0.83)

 < 0.001

1.79 (1.13)

0.97 (0.58)

 < 0.001

 < 0.001

HDL-C (mmol/L)

1.20 (0.36)

1.47 (0.45)

 < 0.001

1.15 (0.32)

1.34 (0.39)

 < 0.001

1.35 (0.39)

1.60 (0.43)

 < 0.001

 < 0.001

LDL-C (mmol/L)

3.30 (1.07)

2.83 (1.05)

 < 0.001

3.29 (1.03)

2.97 (1.03)

 < 0.001

3.32 (1.14)

2.70 (1.04)

 < 0.001

0.001

Albumin (g/L)

47 (4)

47 (4)

 < 0.001

48 (4)

47 (3)

 < 0.001

46 (4)

46 (3)

 < 0.001

 < 0.001

Total bilirubin (μmol/L)

12.3 (5.9)

12.2 (5.8)

0.002

12.8 (6.1)

13.3 (6.3)

 < 0.001

10.8 (4.7)

11.3 (5.0)

 < 0.001

 < 0.001

ALT (IU/L)

32 (24)

18 (13)

 < 0.001

35 (26)

22 (15)

 < 0.001

24 (16)

15 (8)

 < 0.001

 < 0.001

AST (IU/L)

24 (10)

20 (7)

 < 0.001

25 (10)

22 (8)

 < 0.001

22 (8)

19 (6)

 < 0.001

 < 0.001

BUN (mmol/L)

5.1 (1.6)

4.9 (1.7)

 < 0.001

5.2 (1.6)

5.2 (1.7)

0.024

5.0 (1.7)

4.6 (1.6)

 < 0.001

 < 0.001

Creatinine (μmol/L)

73 (19)

66 (23)

 < 0.001

77 (15)

78 (15)

 < 0.001

56 (12)

56 (12)

0.059

 < 0.001

Uric acid (μmol/L)

393 (121)

313 (115)

 < 0.001

414 (110)

368 (96)

 < 0.001

323 (89)

268 (73)

 < 0.001

 < 0.001

WBC (× 109/L)

6.55 (1.97)

5.89 (1.85)

 < 0.001

6.64 (1.96)

6.09 (1.88)

 < 0.001

6.29 (1.94)

5.71 (1.79)

 < 0.001

 < 0.001

RBC (× 1012/L)

5.09 (0.62)

4.77 (0.70)

 < 0.001

5.20 (0.49)

5.12 (0.50)

 < 0.001

4.60 (0.44)

4.49 (0.43)

 < 0.001

 < 0.001

Haemoglobin (g/L)

155 (18)

144 (22)

 < 0.001

159 (14)

157 (13)

 < 0.001

138 (11)

134 (12)

 < 0.001

 < 0.001

Platelet count (× 109/L)

211 (75)

210 (73)

 < 0.001

207 (72)

200 (69)

 < 0.001

226 (82)

219 (76)

 < 0.001

 < 0.001

HCT (%)

45.8 (4.8)

43.1 (6.0)

 < 0.001

46.8 (3.6)

46.3 (3.7)

 < 0.001

41.5 (3.3)

40.6 (3.3)

 < 0.001

 < 0.001

MS (%)

19,310 (53.2)

10,340 (10.1)

 < 0.001

14,013 (50.6)

5675 (11.2)

 < 0.001

5297 (61.4)

4665 (8.9)

 < 0.001

 < 0.001

Dyslipidaemia (%)

29,027 (80.0)

42,854 (41.7)

 < 0.001

22,600 (81.6)

24,797 (49.1)

 < 0.001

6427 (74.5)

18,057 (34.5)

 < 0.001

 < 0.001

Hyperuricaemia (%)

16,325 (45.0)

17,314 (16.8)

 < 0.001

13,605 (49.1)

13,175 (26.1)

 < 0.001

2720 (31.5)

4139 (7.9)

 < 0.001

 < 0.001

  1. Data were described by medians (interquartile range) and proportions (%). P values were derived from Mann–Whitney U test or chi-square test
  2. MAFLD metabolic associated fatty liver disease, BMI body mass index, HDL-C high-density lipoprotein cholesterol, LDL-C low-density lipoprotein cholesterol, ALT alanine aminotransferase, AST aspartate aminotransferase, BUN blood urea nitrogen, WBC white blood cell count, RBC red blood cell count, HCT hematocrit, MS metabolic syndrome
  3. †The P value was calculated from the comparation between the groups of males with MAFLD (27,684) and females with MAFLD (8622)
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BMC Gastroenterology

ISSN: 1471-230X

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