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Table 1 Baseline characteristics of the study participants

From: Prevalence of and risk factors for metabolic associated fatty liver disease in an urban population in China: a cross-sectional comparative study

Characteristics Total (N = 139,170) Male (N = 78,176) Female (N = 60,994) P value
MAFLD (N = 36,306) Non-MAFLD (N = 102,864) P value MAFLD (N = 27,684) Non-MAFLD (N = 50,492) P value MAFLD (N = 8622) Non-MAFLD (N = 52,372) P value
Age (years) 47 (19) 42 (21)  < 0.001 45 (18) 43 (22)  < 0.001 54 (19) 41 (20)  < 0.001  < 0.001
Gender, male (%) 27,684 (76.3) 50,492 (49.1)  < 0.001
BMI (kg/m2) 26.18 (3.41) 22.27 (3.69)  < 0.001 26.35 (3.24) 23.05 (3.43)  < 0.001 25.59 (3.70) 21.48 (3.35)  < 0.001  < 0.001
Waist circumference (cm) 89 (9) 78 (12)  < 0.001 91 (9) 82 (10)  < 0.001 84 (9) 73 (9)  < 0.001  < 0.001
Systolic pressure (mmHg) 130 (24) 117 (22)  < 0.001 130 (22) 121 (21)  < 0.001 132 (28) 112 (21)  < 0.001  < 0.001
Diastolic pressure (mmHg) 81 (15) 72 (14)  < 0.001 82 (15) 75 (15)  < 0.001 78 (16) 69 (13)  < 0.001  < 0.001
Fasting glucose (mmol/L) 5.5 (1.0) 5.1 (0.7)  < 0.001 5.5 (1.0) 5.2 (0.6)  < 0.001 5.6 (1.0) 5.1 (0.6)  < 0.001  < 0.001
Total cholesterol (mmol/L) 5.02 (1.22) 4.64 (1.16)  < 0.001 4.98 (1.20) 4.68 (1.13)  < 0.001 5.13 (1.30) 4.61 (1.18)  < 0.001  < 0.001
Triglycerides (mmol/L) 2.04 (1.43) 1.10 (0.72)  < 0.001 2.12 (1.50) 1.26 (0.83)  < 0.001 1.79 (1.13) 0.97 (0.58)  < 0.001  < 0.001
HDL-C (mmol/L) 1.20 (0.36) 1.47 (0.45)  < 0.001 1.15 (0.32) 1.34 (0.39)  < 0.001 1.35 (0.39) 1.60 (0.43)  < 0.001  < 0.001
LDL-C (mmol/L) 3.30 (1.07) 2.83 (1.05)  < 0.001 3.29 (1.03) 2.97 (1.03)  < 0.001 3.32 (1.14) 2.70 (1.04)  < 0.001 0.001
Albumin (g/L) 47 (4) 47 (4)  < 0.001 48 (4) 47 (3)  < 0.001 46 (4) 46 (3)  < 0.001  < 0.001
Total bilirubin (μmol/L) 12.3 (5.9) 12.2 (5.8) 0.002 12.8 (6.1) 13.3 (6.3)  < 0.001 10.8 (4.7) 11.3 (5.0)  < 0.001  < 0.001
ALT (IU/L) 32 (24) 18 (13)  < 0.001 35 (26) 22 (15)  < 0.001 24 (16) 15 (8)  < 0.001  < 0.001
AST (IU/L) 24 (10) 20 (7)  < 0.001 25 (10) 22 (8)  < 0.001 22 (8) 19 (6)  < 0.001  < 0.001
BUN (mmol/L) 5.1 (1.6) 4.9 (1.7)  < 0.001 5.2 (1.6) 5.2 (1.7) 0.024 5.0 (1.7) 4.6 (1.6)  < 0.001  < 0.001
Creatinine (μmol/L) 73 (19) 66 (23)  < 0.001 77 (15) 78 (15)  < 0.001 56 (12) 56 (12) 0.059  < 0.001
Uric acid (μmol/L) 393 (121) 313 (115)  < 0.001 414 (110) 368 (96)  < 0.001 323 (89) 268 (73)  < 0.001  < 0.001
WBC (× 109/L) 6.55 (1.97) 5.89 (1.85)  < 0.001 6.64 (1.96) 6.09 (1.88)  < 0.001 6.29 (1.94) 5.71 (1.79)  < 0.001  < 0.001
RBC (× 1012/L) 5.09 (0.62) 4.77 (0.70)  < 0.001 5.20 (0.49) 5.12 (0.50)  < 0.001 4.60 (0.44) 4.49 (0.43)  < 0.001  < 0.001
Haemoglobin (g/L) 155 (18) 144 (22)  < 0.001 159 (14) 157 (13)  < 0.001 138 (11) 134 (12)  < 0.001  < 0.001
Platelet count (× 109/L) 211 (75) 210 (73)  < 0.001 207 (72) 200 (69)  < 0.001 226 (82) 219 (76)  < 0.001  < 0.001
HCT (%) 45.8 (4.8) 43.1 (6.0)  < 0.001 46.8 (3.6) 46.3 (3.7)  < 0.001 41.5 (3.3) 40.6 (3.3)  < 0.001  < 0.001
MS (%) 19,310 (53.2) 10,340 (10.1)  < 0.001 14,013 (50.6) 5675 (11.2)  < 0.001 5297 (61.4) 4665 (8.9)  < 0.001  < 0.001
Dyslipidaemia (%) 29,027 (80.0) 42,854 (41.7)  < 0.001 22,600 (81.6) 24,797 (49.1)  < 0.001 6427 (74.5) 18,057 (34.5)  < 0.001  < 0.001
Hyperuricaemia (%) 16,325 (45.0) 17,314 (16.8)  < 0.001 13,605 (49.1) 13,175 (26.1)  < 0.001 2720 (31.5) 4139 (7.9)  < 0.001  < 0.001
  1. Data were described by medians (interquartile range) and proportions (%). P values were derived from Mann–Whitney U test or chi-square test
  2. MAFLD metabolic associated fatty liver disease, BMI body mass index, HDL-C high-density lipoprotein cholesterol, LDL-C low-density lipoprotein cholesterol, ALT alanine aminotransferase, AST aspartate aminotransferase, BUN blood urea nitrogen, WBC white blood cell count, RBC red blood cell count, HCT hematocrit, MS metabolic syndrome
  3. The P value was calculated from the comparation between the groups of males with MAFLD (27,684) and females with MAFLD (8622)