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Table 1 Patient background and clinical parameters

From: Measurement of fasting breath hydrogen concentration as a simple diagnostic method for pancreatic exocrine insufficiency

 

PEI group (n = 30)

Non-PEI group (n = 30)

P value

Age, median [range]

71.0 [46–87]

71.0 [40–81]

1.000

Sex, male: female

24: 6

22: 8

0.542

BMI, median [range]

21.585 [15.99–28.07]

21.090 [15.24–26.38]

0.255

History of alcohol intake, n (%)

19 (63.3)

19 (63.3)

1.000

Heavy drinkers, n (%)

7 (23.3)

1 (3.3)

0.023

Smoking history, n (%)

17 (56.7)

19 (63.3)

0.598

Pancreatic disease

   

 PC, n (%)

11 (36.7)

12 (40.0)

0.791

 CP, n (%)

8 (26.7)

3 (10.0)

0.095

 Other pancreatic disease, n (%)

11 (36.7)

10 (33.3)

0.761

Concomitant diseases

   

 Hypertension, n (%)

10 (33.3)

15 (50.0)

0.190

 Dyslipidemia, n (%)

10 (33.3)

11 (36.7)

0.787

 Diabetes, n (%)

14 (46.7)

13 (43.3)

0.795

Blood test findings

   

 Hb (g/dL) [range]

13.50 [7.9–15.5]

13.50 [10.9–15.9]

0.877

 BUN (mg/dL) [range]

16.05 [3.7–29.2]

15.75 [6.2–26.9]

1.000

 Cre (mg/dL) [range]

0.775 [0.49–1.32]

0.730 [0.42–1.24]

0.225

 TP (g/dL) [range]

7.00 [5.5–8.0]

7.20 [6.2–7.8]

0.716

 Alb (g/dL) [range]

3.95 [1.4–4.5]

4.20 [3.6–4.7]

0.006

 Amy (IU/L) [range]

83.5 [30–374]

74.5 [36–350]

0.877

 Lipase (IU/L) [range]

48.5 [4–781]

34.5 [10–889]

0.706

 HbA1c (NGSP %) [range]

6.65 [4.9–13.7]

6.20 [4.9–10.5]

0.195

 CEA (ng/mL) [range]

3.2 [1.0–44.4]

2.6 [0.7–105.8]

0.261

 CA19-9 (U/mL) [range]

119.50 [< 1–23210]

61.50 [< 1–197000]

0.446

Imaging findings

   

 Pancreatic hypertrophy, n (%)

9 (30.0)

3 (10.0)

0.053

 Calcification, n (%)

4 (13.3)

2 (6.7)

0.389

 Pancreatic cyst, n (%)

6 (20.0)

5 (16.7)

0.739

 MPD dilatation, n (%)

19 (63.3)

13 (43.3)

0.121

 MPD stenosis, n (%)

20 (66.7)

12 (40.0)

0.038

 Normal pancreas, n (%)

0 (0.0)

5 (16.7)

0.020

  1. PEI pancreatic exocrine insufficiency, BMI body mass index, PC pancreatic carcinoma, CP chronic pancreatitis, Hb hemoglobin, BUN blood urea nitrogen, Cre creatinine, TP total protein, Alb albumin, Amy amylase, HbA1c hemoglobin A1c, NGSP national glycohemoglobin standardization program, CEA carcinoembryonic antigen, CA19-9 carbohydrate antigen 19-9, MPD major pancreatic duct