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Table 2 Predictive performances of nomograms, APRI, FIB-4, and GPR for advanced fibrosis (S3–S4) and cirrhosis (S4) (Training cohort)

From: Nomogram for predicting advanced liver fibrosis and cirrhosis in patients with chronic liver disease

Indexes

AUROC (95%CI)

P

Cutoff

Se (%)

Sp (%)

S3–S4

     

 NomogramS3S4

0.83 (0.79–0.87)

< 0.0001

0.41

78.9

79.4

 APRI

0.71 (0.66–0.75)

< 0.0001

0.51

81.5

51.7

 FIB-4

0.68 (0.60–0.70)

< 0.0001

1.48

58.7

70.6

 GPR

0.74 (0.70–0.79)

< 0.0001

0.23

73.2

69.3

S4

     

 NomogramS4

0.88 (0.85–0.91)

< 0.0001

0.91

77.3

85.2

 APRI

0.74 (0.70–0.79)

< 0.0001

0.66

78.2

57.8

 FIB-4

0.78 (0.73–0.81)

< 0.0001

2.34

54.6

89.6

 GPR

0.79 (0.75–0.83)

< 0.0001

0.38

67.3

80.8

  1. AUROC, area under ROC; Se, sensitivity; Sp, specificity
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BMC Gastroenterology

ISSN: 1471-230X

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