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Table 3 Detailed blood/serum/plasma work-up

From: Evaluating the prevalence and severity of NAFLD in primary care: the EPSONIP study protocol

Blood/serum/plasma markers

 

Complete blood count

 

 Hemoglobin, hematocrit, mean corpuscular value, mean corpuscular hemoglobin, mean corpuscular hemoglobin concentration, platelets, white blood cells

 

Liver tests

 

 Albumin, bilirubin, ALT, AST, ALP, γGT, PT(INR), high sensitive C-reactive protein

 

Iron studies

 

 Iron, transferrin saturation, total iron binding capacity, ferritin

 

Serum protein electrophoresis

 

 Antitrypsin, albumin, orosomucoid, haptoglobin, immunoglobulins (IgG, IgM, IgA)

 

Minor kidney function panel

 

 Sodium (Na), potassium (K), creatinine

 

Metabolic tests

 

 Cholesterol, triglycerides, LDL, HDL. fasting glucose, C-peptide, HbA1c, insulin, GAD-antibody

 

Direct alcohol marker

 

 Phosphatidylethanol

 

Auto-antibody screen

 

 ANA, anti-LKM antibody, anti-SM antibody, anti-M antibody

 

Viral serology

 

 HBsAg, anti-HBc, anti-HCV, Hep A IgM, Hep A IgG

 
  1. ALP, alkaline phosphatase; ALT, alanine aminotransferase; ANA, antinuclear antibody; AST, aspartate aminotransferase; GAD, glutamic acid decarboxylase; γGT, gamma-glutamyl transferase; HbA1c, hemoglobin A1c; HBC, hepatitis B core; HBsAg, hepatitis B surface antigen; HCV, hepatitis C virus; HDL, high-density lipoprotein; INR, international normalized ratio; LKM, liver-kidney microsomal; LDL, low-density lipoprotein; M, mitochondrial; PT, prothrombin time; SM, smooth muscle