Plasma interleukin-17 and alpha-fetoprotein combination effectively predicts imminent hepatocellular carcinoma occurrence in liver cirrhotic patients

Table 3 Univariate and multivariate analysis of variables associated with imminent HCC

Item	Odds ratio	Confidence interval		P
Item	Odds ratio	Low	High	P
Univariate analysis
IL-17 (pg/ml)	1	1	1	0.004
Age (years)	1.079	1.017	1.145	0.012
Gender-Male	0.613	0.194	1.936	0.404
HBV	0.341	0.101	1.152	0.083
HCV	6.882	1.831	25.874	0.004
AST (IU/L)	1.003	0.995	1.012	0.443
ALT (IU/L)	1.003	0.996	1.01	0.343
Bilirubin (mg/dL)	0.89	0.369	2.151	0.797
AFP (ng/ml)	1.014	1.004	1.024	0.005
Albumin (g/dL)	0.476	0.17	1.332	0.157
Total protein (g/dL)	0.834	0.401	1.735	0.628
C3 (mg/dL)	0.989	0.96	1.018	0.435
C4 (mg/dL)	0.949	0.867	1.037	0.248
TSH (mU/L)	0.448	0.179	1.121	0.086
Free T4 (ng/dL)	0.099	0.003	3.519	0.205
Sugar AC (mg/dL)	1.004	0.99	1.018	0.578
Glycohemoglobin (%)	1.206	0.864	1.684	0.270
Insulin (mIU/L)	1.014	0.981	1.048	0.409
Insulin/sugar	0.425	0.001	305.942	0.799
HOMA-IR	1.1	0.976	1.241	0.118
Apo A1 (g/L)	2.573	0.811	8.165	0.109
Uric acid (mg/dL)	0.855	0.588	1.243	0.412
HDL (mg/dL)	0.977	0.935	1.02	0.285
VLDL (mg/dL)	1.011	0.978	1.045	0.516
LDL (mg/dL)	0.983	0.961	1.005	0.132
Cholesterol (mg/dL)	0.993	0.977	1.008	0.346
Triglyceride (mg/dL)	1.003	0.995	1.01	0.525
NonHDLC	0.991	0.971	1.011	0.368
Ferritin (ng/mL)	1	0.999	1.001	0.768
Ceruloplasmin (mg/dL)	1.029	0.926	1.145	0.593
Iron (ug/dL)	1.005	0.996	1.014	0.263
TIBC (ug/dL)	1.001	0.99	1.011	0.891
UIBC (ug/dL)	0.997	0.988	1.007	0.591
Multivariate analysis
IL-17 (pg/ml)	1	1	1	0.008
Age (years)	1.081	1.008	1.161	0.030
HCV	4.257	1.059	17.113	0.041
AFP	1.012	1.002	1.023	0.024

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