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Table 3 The comparison between large fragment deletions group and control group

From: Characterization of novel and large fragment deletions in exon 1 of the IL10RA gene in Chinese children with very early onset inflammatory bowel diseases

Patients

Large fragment deletions group

Point mutation group

P

Body weight (kg)

8.1 ± 5.6

5.6 ± 1.6

0.12

Age of disease onset (day)

60.0[7.0,180.0]

14.0[9.0,20.0]

0.27

Age of diagnosis (day)

510.0[97.0,1099.0]

217.0[71.0,259.0]

0.09

Symptom

Diarrhea (day)

60.0[16.0,180.0]

10.0[1.0,22.0]

0.01

Perianal lesions: n (%)

6(85.7)

12(80)

0.26

Oral ulcer: n (%)

1(14.3)

6(40)

0.23

Eczema: n (%)

6(85.7)

5(33.3)

0.02

HFA Z-score

 − 2.9 ± 2.9

 − 2.0 ± 1.1

0.45

WFA Z-score

 − 2.6 ± 2.1

 − 2.3 ± 1.2

0.66

BMI Z-score

Simplified endoscopic score (SES)

22.0 ± 5.5

19.9 ± 8.5

0.57

Laboratory tests

WBC

14.0 ± 4.8

15.1 ± 6.2

0.66

Hb

100.1 ± 19.4

97.9 ± 18.9

0.80

Platelet

518.3 ± 174.5

417.5 ± 152.9

0.18

CRP

19.0[9.0,55.4]

26.5[12.0,71.8]

0.78

ESR

34.0[13.0,50.0]

30.0[18.5,42.5]

0.94

Albumin

30.4 ± 4.1

30.8 ± 5.4

0.89

Prealbumin

105.3 ± 51.8

99.8 ± 61.5

0.84