Relationship between body composition and the histology of non‐alcoholic fatty liver disease: a cross‐sectional study

Table 5 Association of body composition with fibrosis (≥ Stage 1) by multivariate analysis

Index	Model 1		Model 2		Model 3
Index	OR (95 % CI)	P-value	OR (95 % CI)	P-value	OR (95 % CI)	P-value
Muscle mass, kg	0.97 (0.84–1.15)	0.79^a	0.9 (0.77–1.05)	0.18^a	0.92 (0.79–1.07)	0.28^a
Fat mass, kg	1.09 (1.02–1.18)	0.02^b	1.09 (1.02–1.18)	0.01^b	1.1 (1.02–1.18)	0.01^b
BFMI, kg/m²	1.25 (1.03–1.55)	0.02^c	1.27 (1.06–1.55)	0.02^c	1.27 (1.06–1.56)	0.02^c
Visceral fat area, cm²	1.02 (1.002–1.04)	0.03^b	1.02 (1.01–1.05)	< 0.01 ^b	1.02 (1.01–1.05)	< 0.01^b
Waist-hip ratio	2.97 × 10⁵ (1.64–1.52 × 10⁹)	0.04^c	1.09 × 10⁵ (5.21–4.38 × 10⁹)	0.02^c	9.31 × 10⁴ (0.78–3.68 × 10⁸)	0.07^c
SMI/BFMI	0.14 (0.02–0.63)	0.02	0.13 (0.02–0.57)	< 0.01	0.12 (0.02–0.55)	< 0.01

Model 1 was adjusted for age (years) of patient and sex of patient, and alanine aminotransferase (U/L) and creatinine (µmol/L) levels, along with ^afat mass (kg), ^bmuscle mass (kg), and ^cmuscle mass/ht² (kg/m²)
Model 2 was adjusted for age (years) of patient, sex of patient, and hemoglobin A1c levels (%), along with ^afat mass (kg), ^bmuscle mass (kg), and ^cmuscle mass/ht² (kg/m²)
Model 3 was adjusted for age (years) of patient and sex of patient, and total cholesterol (mmol/L) and triglyceride levels (mmol/L), along with ^afat mass (kg), ^bmuscle mass (kg), and ^cmuscle mass/ht² (kg/m²)
OR, odds ratio; CI, confidence interval; BFMI, body fat mass index; SMI, skeletal muscle index; ht², height squared

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