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Table 5 Association of body composition with fibrosis (≥ Stage 1) by multivariate analysis

From: Relationship between body composition and the histology of non‐alcoholic fatty liver disease: a cross‐sectional study

Index Model 1 Model 2 Model 3
OR (95 % CI) P-value OR (95 % CI) P-value OR (95 % CI) P-value
Muscle mass, kg 0.97 (0.84–1.15) 0.79a 0.9 (0.77–1.05) 0.18a 0.92 (0.79–1.07) 0.28a
Fat mass, kg 1.09 (1.02–1.18) 0.02b 1.09 (1.02–1.18) 0.01b 1.1 (1.02–1.18) 0.01b
BFMI, kg/m2 1.25 (1.03–1.55) 0.02c 1.27 (1.06–1.55) 0.02c 1.27 (1.06–1.56) 0.02c
Visceral fat area, cm2 1.02 (1.002–1.04) 0.03b 1.02 (1.01–1.05) < 0.01 b 1.02 (1.01–1.05) < 0.01b
Waist-hip ratio 2.97 × 105 (1.64–1.52 × 109) 0.04c 1.09 × 105 (5.21–4.38 × 109) 0.02c 9.31 × 104 (0.78–3.68 × 108) 0.07c
SMI/BFMI 0.14 (0.02–0.63) 0.02 0.13 (0.02–0.57) < 0.01 0.12 (0.02–0.55) < 0.01
  1. Model 1 was adjusted for age (years) of patient and sex of patient, and alanine aminotransferase (U/L) and creatinine (µmol/L) levels, along with afat mass (kg), bmuscle mass (kg), and cmuscle mass/ht2 (kg/m2)
  2. Model 2 was adjusted for age (years) of patient, sex of patient, and hemoglobin A1c levels (%), along with afat mass (kg), bmuscle mass (kg), and cmuscle mass/ht2 (kg/m2)
  3. Model 3 was adjusted for age (years) of patient and sex of patient, and total cholesterol (mmol/L) and triglyceride levels (mmol/L), along with afat mass (kg), bmuscle mass (kg), and cmuscle mass/ht2 (kg/m2)
  4. OR, odds ratio; CI, confidence interval; BFMI, body fat mass index; SMI, skeletal muscle index; ht2, height squared