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Table 3 Liver stiffness, ICG-R15 and ALBI scores in predicting PHLF

From: Comparison of preoperative two-dimensional shear wave elastography, indocyanine green clearance test and biomarkers for post hepatectomy liver failure prediction in patients with hepatocellular carcinoma

Variable Development cohort Validation cohort
  AUC (95% CI) P value Criterion Accuracy (%) Sensitivity (%) P value Specificity (%) P value
LSV 0.795 (0.714, 0.877)  < 0.0001  > 10.35 kPa 76.9 83.3 0.223 76.3  < 0.0001
ICG-R15 0.619 (0.487, 0.752) 0.109  > 6.4% 66.1 66.7 66.1
ALBI scores 0.686 (0.541, 0.832) 0.012  > − 2.547 70.8 83.3 69.5
  1. In the development cohort, AUCs were compared with AUC = 0.5, in the validation cohort, comparison was conducted between LSV, ICG-R15 and ALBI scores. LSV = liver stiffness value; PHLF = post hepatectomy liver failure; ICG-R15 = indocyanine green retention rate at 15 min; ALBI = albumin-bilirubin; NPV = negative predictive value; PPV = positive predictive value