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Table 3 Clinical correlates of serum adipsin levels with NAFLD-associated metabolic risk factors and liver fibrosis score

From: Association of circulating adipsin with nonalcoholic fatty liver disease in obese adults: a cross-sectional study

Variables

Total

NAFLD

Non-NAFLD

β

p value

Multiple adjusted p value§

β

p value

Multiple adjusted p value§

β

p value

Multiple adjusted p value§

Age(years)

1.192

< 0.001

–

1.430

< 0.001

–

1.033

< 0.001

–

Gender (male n, %)

–

< 0.001

–

–

< 0.001

–

–

< 0.001

–

BMI (kg/m2)

0.352

< 0.001

< 0.001

0.607

< 0.001

< 0.001

0.199

0.046

0.027

Waist circumference (cm)

1.034

< 0.001

0.001

1.557

< 0.001

< 0.001

0.741

0.002

0.045

Systolic BP (mmHg)

1.550

0.003

0.283

1.713

0.025

0.417

1.662

0.016

0.196

Diastolic BP (mmHg)

0.938

0.003

0.033

1.022

0.026

0.092

1.028

0.011

0.039

Total cholesterol (mmol/L)

0.127

0.686

0.523

− 0.019

0.678

0.309

0.049

0.239

0.625

Total triglycerides(mmol/L)

0.008

0.823

0.425

0.013

0.825

0.748

0.032

0.433

0.792

LDL-cholesterol(mmol/L)

0.035

0.218

0.808

0.007

0.870

0.707

0.062

0.092

0.384

HDL-cholesterol(mmol/L)

− 0.025

0.003

0.100

− 0.030

0.009

0.055

− 0.026

0.033

0.172

Fasting glucose (mmol/L)

− 0.235

< 0.001

< 0.001

− 0.433

< 0.001

< 0.001

− 0.050

0.289

0.064

2 h glucose (mmol/L)

− 0.338

0.003

< 0.001

− 0.723

< 0.001

< 0.001

0.056

0.649

0.939

ALT (U/L)

0.114

0.792

0.420

0.310

0.674

0.873

0.227

0.552

0.988

AST (U/L)

0.328

0.127

0.902

0.550

0.114

0.563

0.234

0.323

0.797

GGT (U/L)

− 0.172

0.796

0.060

− 0.621

0.549

0.072

0.596

0.444

0.967

HOMA-IR

− 0.159

0.044

0.024

− 0.373

0.002

0.006

0.074

0.446

0.672

Body fat mass(kg)

0.070

0.654

0.002

0.090

0.715

0.003

0.140

0.459

0.005

FIB-4 value

0.036

0.003

0.728

0.050

0.003

0.450

0.023

0.201

0.741

  1. BMI = body mass index; HOMA-IR = homeostasis model assessment of insulin resistance; FIB-4 = fibrosis-4 index
  2. §Adjusted for age, gender, smoking, alcohol consumption, and physical activity