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Table 3 Clinical correlates of serum adipsin levels with NAFLD-associated metabolic risk factors and liver fibrosis score

From: Association of circulating adipsin with nonalcoholic fatty liver disease in obese adults: a cross-sectional study

Variables Total NAFLD Non-NAFLD
β p value Multiple adjusted p value§ β p value Multiple adjusted p value§ β p value Multiple adjusted p value§
Age(years) 1.192 <0.001 1.430 <0.001 1.033 <0.001
Gender (male n, %) <0.001 <0.001 <0.001
BMI (kg/m2) 0.352 <0.001 <0.001 0.607 <0.001 <0.001 0.199 0.046 0.027
Waist circumference (cm) 1.034 <0.001 0.001 1.557 <0.001 <0.001 0.741 0.002 0.045
Systolic BP (mmHg) 1.550 0.003 0.283 1.713 0.025 0.417 1.662 0.016 0.196
Diastolic BP (mmHg) 0.938 0.003 0.033 1.022 0.026 0.092 1.028 0.011 0.039
Total cholesterol (mmol/L) 0.127 0.686 0.523 − 0.019 0.678 0.309 0.049 0.239 0.625
Total triglycerides(mmol/L) 0.008 0.823 0.425 0.013 0.825 0.748 0.032 0.433 0.792
LDL-cholesterol(mmol/L) 0.035 0.218 0.808 0.007 0.870 0.707 0.062 0.092 0.384
HDL-cholesterol(mmol/L) − 0.025 0.003 0.100 − 0.030 0.009 0.055 − 0.026 0.033 0.172
Fasting glucose (mmol/L) − 0.235 <0.001 <0.001 − 0.433 <0.001 <0.001 − 0.050 0.289 0.064
2 h glucose (mmol/L) − 0.338 0.003 <0.001 − 0.723 <0.001 <0.001 0.056 0.649 0.939
ALT (U/L) 0.114 0.792 0.420 0.310 0.674 0.873 0.227 0.552 0.988
AST (U/L) 0.328 0.127 0.902 0.550 0.114 0.563 0.234 0.323 0.797
GGT (U/L) − 0.172 0.796 0.060 − 0.621 0.549 0.072 0.596 0.444 0.967
HOMA-IR − 0.159 0.044 0.024 − 0.373 0.002 0.006 0.074 0.446 0.672
Body fat mass(kg) 0.070 0.654 0.002 0.090 0.715 0.003 0.140 0.459 0.005
FIB-4 value 0.036 0.003 0.728 0.050 0.003 0.450 0.023 0.201 0.741
  1. BMI = body mass index; HOMA-IR = homeostasis model assessment of insulin resistance; FIB-4 = fibrosis-4 index
  2. §Adjusted for age, gender, smoking, alcohol consumption, and physical activity