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Table 2 Clinical characteristics by quartiles of serum adipsin levels in obese subjects

From: Association of circulating adipsin with nonalcoholic fatty liver disease in obese adults: a cross-sectional study

Variables Serum adipsin level p value for trend§
Quartile 1 Quartile 2 Quartile 3 Quartile 4
Sample size 290 291 291 291  
Serum adipsin (ug/ml) 3.27 ± 0.64 4.45 ± 0.35 5.51 ± 0.46 8.30 ± 2.63 <0.001
Age (years) 51.9 ± 7.2 52.6 ± 7.2 53.6 ± 7.5 54.8 ± 7.1 <.0001
Gender (male n, %) 74 (25.5) 75 (25.8) 75 (25.8) 75 (25.8) 1.000
BMI (kg/m2) 26.9 ± 2.7 27.1 ± 2.6 27.6 ± 3.3 28.0 ± 3.3 <0.001
Waist circumference (cm) 92.2 ± 6.2 93.2 ± 6.9 93.8 ± 7.3 94.6 ± 7.4 <0.001
Current smokers (n, %) 34 (11.7) 36 (12.4) 35 (12.0) 30 (10.3) 0.822
Systolic BP (mmHg) 132.3 ± 16.9 132.4 ± 17.6 133.9 ± 18.4 134.5 ± 18.3 0.864
Diastolic BP (mmHg) 78.5 ± 10.4 79.3 ± 10.2 79.4 ± 11.1 79.6 ± 10.7 0.599
Triglycerides (mmol/L) 1.42 (0.96–2.19) 1.61 (1.13–2.31) 1.43 (0.99–2.19) 1.61 (1.09–2.20) 0.128
Total cholesterol (mmol/L) 5.88 ± 1.08 5.86 ± 1.01 5.90 ± 1.07 5.92 ± 1.10 0.955
LDL-cholesterol (mmol/L) 3.67 ± 1.01 3.59 ± 0.95 3.73 ± 0.92 3.74 ± 1.01 0.491
HDL-cholesterol(mmol/L) 1.39 ± 0.30 1.36 ± 0.31 1.38 ± 0.28 1.34 ± 0.29 0.182
Fasting glucose (mmol/L) 6.40 ± 2.47 6.05 ± 1.52 5.98 ± 1.15 5.89 ± 0.98 <0.001
2-h glucose (mmol/L) 9.23 ± 4.74 8.74 ± 3.65 8.69 ± 3.31 8.57 ± 3.34 0.039
HOMA-IR 3.09 (2.16–4.46) 2.89 (2.16–4.28) 2.65 (1.97–3.76) 2.83(2.03–4.14) 0.035
ALT (U/L) 24.2 ± 12.2 24.9 ± 13.1 25.8 ± 19.8 22.9 ± 12.3 0.107
AST (U/L) 21.7 ± 7.1 22.0 ± 6.5 23.4 ± 9.1 21.9 ± 6.2 0.030
GGT (U/L) 35.1 ± 23.9 35.0 ± 23.4 34.2 ± 23.3 32.3 ± 20.0 0.404
Body fat mass (kg) 23.6 ± 5.1 23.9 ± 5.0 24.2 ± 5.4 24.8 ± 5.6 0.003
FIB-4 value 0.90 ± 0.37 0.94 ± 0.52 0.98 ± 0.37 0.97 ± 0.36 0.608
Metabolic syndrome (n, %) 184 (63.5) 183 (63.1) 181 (62.2) 196 (67.4) 0.579
NAFLD (n, %) 169 (58.3) 175 (60.1) 167 (57.4) 146 (50.2) 0.012
  1. Data are presented as the mean ± SD or median (interquartile range)
  2. BMI = body mass index; HOMA-IR = homeostasis model assessment of insulin resistance; FIB-4 = fibrosis-4 index
  3. §Adjusted for age and gender
  4. p < 0.05compared with Q1 of serum adipsin
  5. p < 0.01compared with Q1 of serum adipsin