Variables | Serum adipsin level | p value for trend§ | |||
---|---|---|---|---|---|
Quartile 1 | Quartile 2 | Quartile 3 | Quartile 4 | ||
Sample size | 290 | 291 | 291 | 291 | Â |
Serum adipsin (ug/ml) | 3.27 ± 0.64 | 4.45 ± 0.35 | 5.51 ± 0.46 | 8.30 ± 2.63 | < 0.001 |
Age (years) | 51.9 ± 7.2 | 52.6 ± 7.2 | 53.6 ± 7.5‡ | 54.8 ± 7.1‡ | < .0001 |
Gender (male n, %) | 74 (25.5) | 75 (25.8) | 75 (25.8) | 75 (25.8) | 1.000 |
BMI (kg/m2) | 26.9 ± 2.7 | 27.1 ± 2.6 | 27.6 ± 3.3†| 28.0 ± 3.3‡ | < 0.001 |
Waist circumference (cm) | 92.2 ± 6.2 | 93.2 ± 6.9 | 93.8 ± 7.3†| 94.6 ± 7.4‡ | < 0.001 |
Current smokers (n, %) | 34 (11.7) | 36 (12.4) | 35 (12.0) | 30 (10.3) | 0.822 |
Systolic BP (mmHg) | 132.3 ± 16.9 | 132.4 ± 17.6 | 133.9 ± 18.4 | 134.5 ± 18.3 | 0.864 |
Diastolic BP (mmHg) | 78.5 ± 10.4 | 79.3 ± 10.2 | 79.4 ± 11.1 | 79.6 ± 10.7 | 0.599 |
Triglycerides (mmol/L) | 1.42 (0.96–2.19) | 1.61 (1.13–2.31) | 1.43 (0.99–2.19) | 1.61 (1.09–2.20) | 0.128 |
Total cholesterol (mmol/L) | 5.88 ± 1.08 | 5.86 ± 1.01 | 5.90 ± 1.07 | 5.92 ± 1.10 | 0.955 |
LDL-cholesterol (mmol/L) | 3.67 ± 1.01 | 3.59 ± 0.95 | 3.73 ± 0.92 | 3.74 ± 1.01 | 0.491 |
HDL-cholesterol(mmol/L) | 1.39 ± 0.30 | 1.36 ± 0.31 | 1.38 ± 0.28 | 1.34 ± 0.29 | 0.182 |
Fasting glucose (mmol/L) | 6.40 ± 2.47 | 6.05 ± 1.52‡ | 5.98 ± 1.15‡ | 5.89 ± 0.98‡ | < 0.001 |
2-h glucose (mmol/L) | 9.23 ± 4.74 | 8.74 ± 3.65 | 8.69 ± 3.31†| 8.57 ± 3.34†| 0.039 |
HOMA-IR | 3.09 (2.16–4.46) | 2.89 (2.16–4.28) | 2.65 (1.97–3.76) †| 2.83(2.03–4.14) | 0.035 |
ALT (U/L) | 24.2 ± 12.2 | 24.9 ± 13.1†| 25.8 ± 19.8 | 22.9 ± 12.3 | 0.107 |
AST (U/L) | 21.7 ± 7.1 | 22.0 ± 6.5 | 23.4 ± 9.1 | 21.9 ± 6.2 | 0.030 |
GGT (U/L) | 35.1 ± 23.9 | 35.0 ± 23.4 | 34.2 ± 23.3 | 32.3 ± 20.0 | 0.404 |
Body fat mass (kg) | 23.6 ± 5.1 | 23.9 ± 5.0 | 24.2 ± 5.4 | 24.8 ± 5.6‡ | 0.003 |
FIB-4 value | 0.90 ± 0.37 | 0.94 ± 0.52 | 0.98 ± 0.37 | 0.97 ± 0.36 | 0.608 |
Metabolic syndrome (n, %) | 184 (63.5) | 183 (63.1) | 181 (62.2) | 196 (67.4) | 0.579 |
NAFLD (n, %) | 169 (58.3) | 175 (60.1) | 167 (57.4) | 146 (50.2) †| 0.012 |