Table 1 Clinical characteristics of obese subjects by non-alcoholic fatty liver disease (NAFLD)
Variables | Overall | NAFLD | Non-NAFLD | p value |
|---|---|---|---|---|
Sample size | 1163 | 657 | 506 | Â |
Age (years) | 53.2 ± 7.3 | 53.7 ± 7.3 | 52.6 ± 7.2 | 0.008 |
Gender (male n, %) | 299 (25.7) | 207 (34.0) | 92 (21.9) | < 0.001 |
BMI (kg/m2) | 27.4 ± 3.0 | 28.2 ± 3.1 | 26.4 ± 2.5 | < 0.001 |
Waist circumference (cm) | 93.4 ± 7.0 | 95.3 ± 7.2 | 91.1 ± 5.9 | < 0.001 |
Current smokers (n, %) | 135(12.6) | 91(14.5) | 44(10.2) | 0.006 |
Systolic BP (mmHg) | 133.3 ± 17.8 | 136.3 ± 17.7 | 129.4 ± 17.3 | < 0.001 |
Diastolic BP (mmHg) | 79.2 ± 10.6 | 81.1 ± 10.6 | 76.7 ± 10.1 | < 0.001 |
Triglycerides (mmol/L) | 1.53 (1.03–2.22) | 1.84 (1.32–2.57) | 1.18 (0.86–1.71) | < 0.001 |
Total cholesterol (mmol/L) | 5.89 ± 1.07 | 6.00 ± 1.07 | 5.74 ± 1.05 | < 0.001 |
LDL- cholesterol (mmol/L) | 3.68 ± 0.97 | 3.72 ± 1.01 | 3.64 ± 0.92 | 0.161 |
HDL-cholesterol (mmol/L) | 1.37 ± 0.30 | 1.31 ± 0.27 | 1.45 ± 0.31 | < 0.001 |
Fasting glucose (mmol/L) | 6.08 ± 1.64 | 6.28 ± 1.90 | 5.82 ± 1.19 | < 0.001 |
2-h glucose (mmol/L) | 8.81 ± 3.81 | 9.58 ± 4.13 | 7.80 ± 3.07 | < 0.001 |
HOMA-IR | 2.88 (2.09–4.16) | 3.46 (2.49–5.00) | 2.38 (1.68–3.24) | < 0.001 |
ALT (U/L) | 24.4 ± 14.7 | 27.8 ± 17.0 | 20.1 ± 9.5 | < 0.001 |
AST (U/L) | 22.2 ± 7.3 | 23.4 ± 8.1 | 20.7 ± 5.9 | < 0.001 |
GGT (U/L) | 34.2 ± 22.7 | 38.8 ± 24.0 | 28.2 ± 19.4 | < 0.001 |
Serum adipsin (ug/ml) | 5.39 ± 2.32 | 5.24 ± 1.97 | 5.57 ± 2.70 | 0.017 |
Body fat mass(kg) | 24.1 ± 5.3 | 25.0 ± 5.6 | 23.0 ± 4.7 | < 0.001 |
FIB-4 value | 0.95 ± 0.41 | 0.93 ± 0.38 | 0.97 ± 0.45 | 0.158 |
Liver fibrosis (n, %) | Â | Â | Â | 0.317 |
FIB-4 Low | 991 (85.2) | 566 (86.2) | 425 (84.0) | Â |
FIB-4 Intermediate | 167 (14.4) | 87 (13.2) | 80 (15.8) | Â |
FIB-4 High | 5 (0.4) | 4 (0.6) | 1 (0.2) | Â |