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Table 2 Univariate analysis of factors associated with RE

From: Study on the relationship of depression, anxiety, lifestyle and eating habits with the severity of reflux esophagitis

Risk factors

Number of cases (%)

p value*

RE group (n = 361)

Control group (n = 328)

Education level

   

Up to junior high school

95 (26.3)

25 (7.6)

 < 0.001**

Higher than junior high school

266 (73.7)

303 (92.4)

 

Marital status

   

Single

17 (4.7)

19 (5.8)

0.524

Married

324 (89.8)

293 (89.3)

0.857

Divorced/Widowed

20 (5.5)

16 (4.9)

0.697

Job

   

Unemployed

20 (5.5)

16 (4.9)

0.697

Self-employed

32 (8.9)

22 (6.7)

0.293

Employed

309 (85.6)

290 (88.4)

0.273

Domicile

   

Rural

41 (11.4)

28 (8.5)

0.218

Urban

320 (88.6)

300 (91.5)

 

Monthly income

   

 < $800

55 (15.2)

42 (12.8)

0.360

$800–1500

199 (55.1)

196 (59.8)

0.220

 > $1500

107 (29.6)

90 (27.4)

0.523

Smoking

84 (23.3)

50 (15.2)

0.008**

Alcohol drinking

75 (20.8)

64 (19.5)

0.170

Drinking strong tea

87 (24.1)

35 (10.7)

 < 0.001**

Drinking coffee

48 (13.3)

60 (18.3)

0.072

Preference for sweets

172 (47.6)

86 (26.2)

 < 0.001**

Overeating

200 (55.4)

55 (16.8)

 < 0.001**

Short interval between dinner and sleep

192 (53.2)

72 (22.0)

 < 0.001**

Preference for spicy foods

128 (35.5)

120 (36.6)

0.758

Preference for acidic foods

74 (20.5)

20 (6.1)

 < 0.001**

Preference for noodles

193 (53.5)

88 (26.8)

 < 0.001**

Preference for fried and fatty foods

93 (25.8)

59 (18.0)

0.014**

Preference for fruits

93 (25.8)

59 (18.0)

0.014**

Constipation

76 (21.1)

28 (8.5)

 < 0.001**

Sleeping on a low pillow

159 (44.0)

49 (14.9)

 < 0.001**

BMI (kg/m2)

   

Normal weight (18.5–23.9)

196 (54.3)

231 (70.4)

 < 0.001**

Overweight (24–27.9)

115 (31.9)

76 (23.2)

0.011**

Obese (≥ 28)

50 (13.9)

21 (6.4)

0.001**

Comorbidities

   

Hypertension

104 (28.8)

42 (12.8)

 < 0.001**

Ischemic heart disease

29 (8.0)

15 (4.6)

0.064

Diabetes mellitus

34 (9.4)

20 (6.1)

0.106

Hyperlipidemia

47 (13.0)

30 (9.1)

0.107

Asthma

15 (4.2)

6 (1.8)

0.076

Current medications (oral)

   

Calcium channel blockers

58 (16.1)

19 (5.8)

 < 0.001**

Low-dose aspirin

33 (9.1)

18 (5.5)

0. 068

Clopidogrel

18 (5.0)

9 (2.7)

0.130

Statins

45 (12.5)

29 (8.8)

0.125

Angiotensin receptor blockers

43 (11.9)

25 (7.6)

0. 060

Hypoglycemic agents

32 (8.9)

18 (5.5)

0.088

Theophylline

10 (2.8)

4 (1.2)

0.150

β-receptor blockers

46 (12.7)

30 (9.1)

0.626

  1. BMI body mass index. *p-values were derived from Chi-square test. **Significant at the level of p < 0.05