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Table 2 Characteristics of patients and lesions

From: Differentiation of small (≤ 3 cm) hepatocellular carcinomas from benign nodules in cirrhotic liver: the added additive value of MRI-based radiomics analysis to LI-RADS version 2018 algorithm

Parameters

HCCs

Benign nodules

P value

Patient-wise analysis

Number

111

39

 

Age, median [range] (years)

55 [35–81]

59 [41–82]

0.198

Male/female

97/14

34/5

0.706

Child–Pugh

  

NA

A

56

19

 

B

45

14

 

C

10

6

 

AFPa

   

Patients with high AFP serumb

45

11

NA

Patients with AFP serum > 200 ng/ml

24

2

NA

Etiology of liver cirrhosisc

  

NA

HBV

86

34

 

HCV

18

3

 

Ethanol

20

6

 

Number of nodules/patient

  

NA

One nodule

110

34

 

Two nodules

1

5

 

Lesion-wise analysis

   

Number

112

44

NA

Histopathologic feature of lesions

   

Well-differentiated HCC

47

0

 

Moderately/Poorly differentiated HCC

75

0

NA

Dysplastic nodule

0

39

 

Regenerative nodule

0

5

 

Nodule size, median [range] (cm)

2.1 [0.9–3.0]

1.7 [0.6–2.9]

0.027

  1. Continuous variables are expressed as a median/range and qualitative variables as the total count
  2. NA not assessment, AFP alpha-fetoprotein
  3. a43 missing data
  4. bHigh AFP serum means above the upper normal limit
  5. cA patient could have multiple etiologies