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Table 3 Immunohistochemistry analysis of the expression levels of 27 markers in tumour tissue compared to non-tumor

From: mRNA profiling of a well-differentiated G1 pancreatic NET correlates with immunohistochemistry profile: a case report

Marker Expression in Non-Tumour Tissue Expression in Tumour Tissue
CgA  +  +  + 
synaptophysin
NSE  +  +  + 
CD56  +   +  + 
Ki-67  + 
PCNA  + 
DAXX  +  +  + 
CD24  +  +  + 
CD44  +   +  +  + 
CD31  + 
CD45  +  +  + 
Vimentin  +  + 
β-catenin  +  +  + 
MENA  +   + 
CD49  +   + 
Laminin  +  +  +   + 
ECAD  +   +  + 
PCAD
EpCAM  +   + 
CDX2
PDX1  +  +   +  +  + 
CD14  +  +   + 
CK6  +  +   + 
CK7  +  + 
CK13  +  + 
CK20  +  + 
P53  +  + 
  1. *represents a similar expression pattern as obtained with mRNA analysis. + and − represent the increase and decrease in expression of marker in tumour tissue in comparison to the normal sample
  2. −: Absence of marker expression; + :1- 25% field positive for marker expression; + + : 25–50% field positive for marker expression; + + + : > 50% field positive for marker expression