mRNA profiling of a well-differentiated G1 pancreatic NET correlates with immunohistochemistry profile: a case report

Table 3 Immunohistochemistry analysis of the expression levels of 27 markers in tumour tissue compared to non-tumor

Marker	Expression in Non-Tumour Tissue	Expression in Tumour Tissue
CgA	−	+ + +
synaptophysin	−	−
NSE	−	+ + +
CD56	+	+ +
Ki-67	−	+
PCNA	−	+
DAXX	−	+ + +
CD24	−	+ + +
CD44	+	+ + +
CD31	−	+
CD45	−	+ + +
Vimentin	−	+ +
β-catenin	−	+ + +
MENA	+	+
CD49	+	+
Laminin	+ + +	+
ECAD	+	+ +
PCAD	−	−
EpCAM	+	+
CDX2	−	−
PDX1	+ +	+ + +
CD14	+ +	+
CK6	+ +	+
CK7	+ +	−
CK13	+ +	−
CK20	−	+ +
P53	−	+ +

^*represents a similar expression pattern as obtained with mRNA analysis. + and − represent the increase and decrease in expression of marker in tumour tissue in comparison to the normal sample
−: Absence of marker expression; + :1- 25% field positive for marker expression; + + : 25–50% field positive for marker expression; + + + : > 50% field positive for marker expression

ISSN: 1471-230X