Table 1 Comparison of clinical and liver chemistry profile of BA versus Non-BA patients
From: Role of percutaneous liver biopsy in infantile cholestasis: cohort from Arabs
Variables | BA group (n = 22) | Non-BA group (n = 100) | P value |
|---|---|---|---|
Gender male:female | 1.3 | 1.8 | 0.172 |
Birth weight (kg) ± SD | 2.83 (± 0.40) | 2.74 (± 0.64) | 0.496 |
Gestational age (preterm) | 3 (10%) | 10 (10%) | 0.831 |
Mean Age at onset of jaundice (days) ± SD | 5.53 (± 8.41) | 23.79 (± 48.57) | 0.059 |
Mean Age at biopsy (days) ± SD | 78.76 (± 38.04) | 150.75 (± 184.86) | 0.051 |
Pale stool | 22 (100%) | 42 (42%) | < 0.001 |
Hepatomegaly | 16 (72%) | 65 (65%) | 0.696 |
Labs (Mean ± SD) | |||
STB (µmol/L) | 189.97 (± 64.43) | 156.26 (± 91.14) | 0.049 |
Direct bilirubin (µmol/L) | 156.13 (± 51.77) | 127.32 (± 71.50) | 0.056 |
ALT (U/L) | 244.88 (± 144.85) | 260.64 (± 283.33) | 0.787 |
AST (U/L) | 378.72 (± 250.19) | 348.77 (± 282.97) | 0.624 |
GGT (U/L) | 640.88 (± 507.79) | 308.35 (± 392.31) | < 0.001 |
Alkaline phosphatase (U/L) | 803.8 (± 416.43) | 746.98 (± 465.23) | 0.572 |