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Table 1 Basic characteristics of the study population

From: Higher frailty burden in older adults with chronic constipation

 

Without chronic constipation (n = 1141)

With chronic constipation (n = 136)

P value

Age, years

75.1 ± 6.2

77.1 ± 6.3

.001

Men

472 (41.4%)

49 (36.0%)

.231

Education level, years

6.1 ± 3.7

5.0 ± 3.2

.001

Monthly income < USD 500, n (%)

52 (4.6%)

8 (5.9%)

.490

Body mass index, kg/m2

25.1 ± 3.5

25.1 ± 3.6

.896

Multimorbidity

560 (49.1%)

85 (62.5%)

.003

 Hypertension

692 (60.7%)

93 (68.4%)

.080

 Diabetes

253 (22.2%)

40 (29.4%)

.058

 Malignancy

76 (6.7%)

15 (11.0%)

.061

 Myocardial infarction

52 (4.6%)

11 (8.1%)

.072

Polypharmacy

239 (21.0%)

47 (34.6%)

< .001

Cognitive dysfunction

292 (25.6%)

45 (33.1%)

.061

Depression

77 (6.8%)

12 (8.8%)

.369

Fall history in the past year

39 (3.4%)

6 (4.4%)

.552

Risk of malnutrition

410 (35.9%)

64 (47.1%)

.011

ADL disability

317 (27.8%)

42 (30.9%)

.447

IADL disability

230 (20.2%)

36 (26.5%)

.087

CHS frailty scale score

1.3 ± 1.1

1.8 ± 1.1

< .001

CHS frailty phenotype

  

< .001

 Robust

329 (28.8%)

15 (11.0%)

 

 Pre-frail

653 (57.2%)

85 (62.5%)

 

 Frail

159 (13.9%)

36 (26.5%)

 

Component of CHS frailty phenotype

 Exhaustion

145 (12.7%)

25 (18.4%)

.088

 Low activity level

285 (25.0%)

58 (42.6%)

< .001

 Slowness

389 (34.1%)

80 (58.8%)

< .001

 Weakness

548 (48.0%)

74 (54.4%)

.188

 Weight loss

66 (5.8%)

6 (4.4%)

.646

Self-reported constipation

236 (20.7%)

88 (64.7%)

< .001

Use of stool softener or laxatives

85 (7.4%)

47 (34.6%)

< .001

  1. Values are expressed as mean ± standard deviation or frequency (%)
  2. CHS frailty phenotype is defined according to the sum of the presence of the phenotypes; robust (0 point), prefrail (1–2 points), or frail (3–5 points)
  3. ADL activities of daily living, CHS Cardiovascular Health Study, IADL instrumental activities of daily living