From: Symptoms and biomarkers associated with undiagnosed celiac seropositivity
N measurements (n cases/ n controls) | Cases: Celiac disease antibody positive participantsa | Controls | OR (95% CI)b | |
---|---|---|---|---|
Number of participants | 169 | 676 | ||
Median (5%/95%) | Median (5%/95%) | |||
Cholesterol (mmol/L)* | 790 (cases:158/controls:632) | 5.5 (3.7/8.0) | 5.7 (4.1/7.8) | |
1st quartile | 1.56 (0.92–2.62) | |||
2nd quartile | 1.02 (0.60–1.74) | |||
3rd quartile | 0.84 (0.50–1.43) | |||
4th quartile | Ref | |||
% (n/N) | % (n/ total N ) | |||
Cholesterol under 5 mmol/L | 37.3 (59/158) | 28.3 (179/632) | 1.60 (1.08–2.37) | |
Median (5%/95%) | Median (5%/95%) | |||
Hemoglobin (mmol/L)* | 235 (cases:48/controls:187) | 8.4 (7.2/9.8) | 8.6 (7.6/9.9) | |
1st quartile | 1.44 (0.47–4.40) | |||
2nd quartile | 0.63 (0.21–1.83) | |||
3rd quartile | 0.63 (0.21–1.88) | |||
4th quartile | Ref | |||
% (n/ total N ) | % (n/N) | |||
Low hemoglobinc | 12.5 (6/48) | 4.3 (8/187) | 3.82 (1.14–12.79) | |
Median (5%/95%) | Median (5%/95%) | |||
Fasting blood glucose (mmol/L)* | 549 (cases:110/controls:439) | 4.8 (4.0/6.0) | 4.8 (3.9/6.3) | |
1st quartile | 0.84 (0.46–1.54) | |||
2nd quartile | 1.00 (0.56–1.79) | |||
3rd quartile | 0.68 (0.38–1.23) | |||
4th quartile | Ref | |||
Fasting blood glucose over 7 mmol/L | 1.8 (2/110) | 2.5 (11/439) | 0.69 (0.14–3.48) | |
Median (5%/95%) | Median (5%/95%) | |||
HbA1c (%)* | 474 (cases:95/controls:379) | 5.8 (4.9/6.5) | 5.8 (5.0/6.5) | |
1st quartile | 1.26 (0.61–2.57) | |||
2nd quartile | 1.01 (0.53–1.92) | |||
3rd quartile | 1.14 (0.62–2.08) | |||
4th quartile | Ref | |||
Median (5%/95%) | Median (5%/95%) | |||
Ferritin (µg/L)* | 455 (cases:92/controls:363) | 74.5 (6.0/311.0) | 78.0 (8.0/298.0) | |
1st quartile | 1.41 (0.65–3.05) | |||
2nd quartile | 0.72 (0.36–1.43) | |||
3rd quartile | 0.69 (0.35–1.34) | |||
4th quartile | Ref | |||
ALAT (Alanine transaminase)* (U/L) | 465 (cases:94/controls:371) | 10.8 (6.6/33.0) | 10.2(6.6/32.0) | |
1st quartile | 0.67 (0.17–2.73) | |||
2nd quartile | 0.63 (0.15–2.56) | |||
3rd quartile | 1.43 (0.41–4.07) | |||
4th quartile | Ref | |||
ASAT (Aspartate aminotransferase) (U/L)* | 35 (cases:7/controls:28) | 20.0 (14.0/28.0) | 17.5 (13.0/38.0) | |
1st quartile | 0.63 (0.08–5.26) | |||
2nd quartile | 0.37 (0.04–4.01) | |||
3rd quartile | 0.34 (0.03–4.41) | |||
4th quartile | Ref | |||
Alkaline phosphatase (ALP)* (U/L) | 385 (cases:77/controls:308) | 48.0 (28.2/90.0) | 44.4 (28.2/72.0) | |
1st quartile | 0.69 (0.34–1.40) | |||
2nd quartile | 0.63 (0.32–1.25) | |||
3rd quartile | 0.60 (0.30–1.20) | |||
4th quartile | Ref | |||
% (n/ total N ) | % (n/ total N ) | |||
Elevated liver parameters (ASAT/ALAT/ALP)d | 1.0 (1/102) | 2.2 (9/407) | 0.42 (0.05–3.48) | |
Median (5%/95%) | Median (5%/95%) | |||
Vitamin D (nmol/L)* | 474 (cases:95/controls:379) | 50.0 (10.0/107.0) | 54.0 (13.0/102.0) | |
1st quartile | 1.21 (0.63–2.30) | |||
2nd quartile | 1.41 (0.76–2.65) | |||
3rd quartile | 1.05 (0.55–2.01) | |||
4th quartile | Ref | |||
Vitamin B12 (pmol/L)* | 385 (cases:77/controls:308) | 286.3 (159.4/513.6) | 295.9 (170.5/492.2) | |
1st quartile | 1.22 (0.63–2.38) | |||
2nd quartile | 0.81 (0.39–1.69) | |||
3rd quartile | 0.64 (0.30–1.36) | |||
4th quartile | Ref |