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Table 1 Comparison of baseline characteristics between treatment groups

From: A randomised placebo controlled trial of VSL#3® probiotic on biomarkers of cardiovascular risk and liver injury in non-alcoholic fatty liver disease

Measurements

Mean baseline pre-VSL#3® (n = 19)

Mean baseline pre-placebo (n = 16)

p value

Age (y)

57 ± 8

58 ± 7

0.96

Gender (male/female)b

15/4

13/3

0.91

Duration NAFLD (y)b

0.25 IQR 2.0

1.0 IQR 1.5

0.27

No. of T2DM (or IFG)b

15

11

0.61

No. of smokersb

2

2

0.94

Alcohol (units/wk)b

1 IQR 8

6 IQR 8

0.10

BMI (kg/m2)b

31.2 IQR 9.1

31.9 IQR 4.0

0.57

Waist circumference (cm)

112.2 ± 14.3

111.2 ± 10.7

0.81

Systolic BP (mmHg)

133 ± 13

135 ± 12

0.56

Diastolic BP (mmHg)

82 ± 8

82 ± 7

0.91

Total cholesterol (mmol/l)

4.51 ± 1.38

4.31 ± 0.85

0.61

HDL (mmol/l)b

0.98 IQR 0.35

0.95 IQR 0.54

0.66

LDL (mmo/l)

2.58 ± 1.18

2.42 ± 0.70

0.64

Triglycerides (mmol/l)b

1.80 IQR 0.45

1.80 IQR 1.27

0.73

HbA1c (mmol/mol)b

54 IQR 17

47 IQR 19

0.23

HOMA-IRb

1.6 IQR 1.7

3.0 IQR 1.8

0.04a

ALT (iu/L)b

43 IQR 56

51 IQR 30

0.96

AST (iu/L)

40 ± 16

40 ± 15

0.99

  1. ap < 0.05
  2. bMann Whitney U test for non-parametric data one missing value on LDL as triglyceride (> 4.5 mmol/l) was too high for LDL calculation