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Table 1 Baseline characteristics of the patients and lesions

From: Impact of obesity in colorectal endoscopic submucosal dissection: single-center retrospective cohort study

 

Total

Control

Overweight

Obese

P value

(BMI < 25 kg/m2)

(25 kg/m2 ≤ BMI < 30 kg/m2)

(BMI ≥ 30 kg/m2)

Patients (n)

523

407

98

18

 

Age (median [IQR*1])

70.0 (62.5–77.0)

71.0 (63.0–77.0)

69.5 (61.5–75.0)

67.5 (59.3–80.0)

0.354

Sex, male (n)

300 (57.4%)

227 (55.8%)

64 (65.3%)

9 (50.0%)

0.188

BMI*2 (kg/m2, median [IQR])

22.8 (20.3–24.8)

21.7 (19.8–23.4)

26.3 (25.6–27.3)

32.4 (31.2–34.0)

 < 0.001

Cecal insertion time*3 (min, median [IQR])

5.5 (4.0–7.0)

6.0 (4.0–7.5)

5.0 (3.0–6.0)

5.0 (4.0–5.25)

0.086

Comorbidities (n)

 Hypertension

236 (45.1%)

174 (42.8%)

53 (54.1%)

9 (50.0%)

0.118

 Diabetes

66 (12.6%)

46 (11.3%)

18 (18.4%)

2 (11.1%)

0.164

 Cardiovascular disease

17 (3.3%)

14 (3.4%)

2 (2.0%)

1 (5.6%)

0.668

 Cerebrovascular disease

53 (10.1%)

42 (11.5%)

7 (7.1%)

4 (22.2%)

0.145

 Liver cirrhosis

9 (1.7%)

7 (1.7%)

2 (2.0%)

0 (0.0%)

0.829

 Chronic renal failure

15 (2.9%)

14 (3.4%)

1 (1.0%)

0 (0.0%)

0.331

 Respiratory disease*4

21 (4.0%)

19 (4.7%)

2 (2.0%)

0 (0.0%)

0.334

Antithrombotic medication (n)

90 (17.2%)

71 (17.4%)

15 (15.3%)

4 (22.2%)

0.747

Lesion (n)

586

458

108

20

 

Location (n)

 

0.809

 Cecum

84 (14.3%)

66 (14.4%)

13 (12.0%)

5 (25.0%)

 

 Ascending

141 (24.1%)

108 (23.6%)

28 (25.9%)

5 (25.0%)

 

 Transverse

131 (22.4%)

100 (21.8%)

26 (24.1%)

5 (25.0%)

 

 Descending

47 (8.0%)

35 (7.6%)

11 (10.2%)

1 (5.0%)

 

 Sigmoid

84 (14.3%)

66 (14.4%)

15 (13.9%)

3 (15.0%)

 

 Rectum

99 (16.9%)

83 (18.1%)

15 (13.9%)

1 (5.0%)

 

Macroscopic type (n)

 

0.795

 Protruded

99 (16.9%)

78 (17.0%)

17 (15.7%)

4 (20.0%)

 

 Elevated

482 (82.2%)

375 (81.9%)

91 (84.3%)

16 (80.0%)

 

 Depressed

5 (0.9%)

5 (1.1%)

0 (0.0%)

0 (0.0%)

 

Pathologycal diagnosis (n)

 

0.636

 Adenoma

367 (62.6%)

293 (64.0%)

64 (59.3%)

10 (50.0%)

 

 Tis

165 (28.2%)

123 (26.9%)

34 (31.5%)

8 (40.0%)

 

 T1

54 (9.2%)

42 (9.2%)

10 (9.3%)

2 (10.0%)

 
  1. *1 Interquartile range
  2. *2 Body mass index
  3. *3 Cecal insertion time of the colonoscopy for pre-ESD observation
  4. *4 interstitial lung disease or chronic obstructive pulmonary disease